| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22114.1 | EKY22115.1 | HMPREF0216_03444 | HMPREF0216_03445 | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | Putative riboflavin biosynthesis protein RibF; KEGG: cpf:CPF_1936 2.4e-47 ribF, ribC; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | 0.989 |
| EKY22114.1 | EKY28433.1 | HMPREF0216_03444 | HMPREF0216_00784 | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.654 |
| EKY22114.1 | EKY28434.1 | HMPREF0216_03444 | HMPREF0216_00785 | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | Riboflavin synthase, alpha subunit. | 0.872 |
| EKY22114.1 | ribBA | HMPREF0216_03444 | HMPREF0216_00786 | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.889 |
| EKY22114.1 | ribH | HMPREF0216_03444 | HMPREF0216_00787 | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.757 |
| EKY22115.1 | EKY22114.1 | HMPREF0216_03445 | HMPREF0216_03444 | Putative riboflavin biosynthesis protein RibF; KEGG: cpf:CPF_1936 2.4e-47 ribF, ribC; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | 0.989 |
| EKY22115.1 | EKY28433.1 | HMPREF0216_03445 | HMPREF0216_00784 | Putative riboflavin biosynthesis protein RibF; KEGG: cpf:CPF_1936 2.4e-47 ribF, ribC; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.606 |
| EKY22115.1 | EKY28434.1 | HMPREF0216_03445 | HMPREF0216_00785 | Putative riboflavin biosynthesis protein RibF; KEGG: cpf:CPF_1936 2.4e-47 ribF, ribC; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | Riboflavin synthase, alpha subunit. | 0.872 |
| EKY22115.1 | ribBA | HMPREF0216_03445 | HMPREF0216_00786 | Putative riboflavin biosynthesis protein RibF; KEGG: cpf:CPF_1936 2.4e-47 ribF, ribC; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.874 |
| EKY22115.1 | ribH | HMPREF0216_03445 | HMPREF0216_00787 | Putative riboflavin biosynthesis protein RibF; KEGG: cpf:CPF_1936 2.4e-47 ribF, ribC; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.757 |
| EKY22283.1 | EKY26139.1 | HMPREF0216_03327 | HMPREF0216_02178 | Pyruvate kinase; KEGG: cbe:Cbei_0485 5.0e-182 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50. | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | 0.824 |
| EKY22283.1 | EKY27727.1 | HMPREF0216_03327 | HMPREF0216_01201 | Pyruvate kinase; KEGG: cbe:Cbei_0485 5.0e-182 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50. | Pyruvate kinase; KEGG: cbe:Cbei_4851 1.2e-187 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | 0.785 |
| EKY22283.1 | EKY28433.1 | HMPREF0216_03327 | HMPREF0216_00784 | Pyruvate kinase; KEGG: cbe:Cbei_0485 5.0e-182 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.788 |
| EKY22283.1 | EKY28434.1 | HMPREF0216_03327 | HMPREF0216_00785 | Pyruvate kinase; KEGG: cbe:Cbei_0485 5.0e-182 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50. | Riboflavin synthase, alpha subunit. | 0.703 |
| EKY22283.1 | rpmE | HMPREF0216_03327 | HMPREF0216_01291 | Pyruvate kinase; KEGG: cbe:Cbei_0485 5.0e-182 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50. | Ribosomal protein L31; Binds the 23S rRNA. | 0.448 |
| EKY23308.1 | EKY28434.1 | HMPREF0216_02978 | HMPREF0216_00785 | Pyridine nucleotide-disulfide oxidoreductase; KEGG: ctc:CTC01178 1.1e-209 NADH oxidase K00356; Psort location: Cytoplasmic, score: 9.67. | Riboflavin synthase, alpha subunit. | 0.813 |
| EKY23308.1 | rpmE | HMPREF0216_02978 | HMPREF0216_01291 | Pyridine nucleotide-disulfide oxidoreductase; KEGG: ctc:CTC01178 1.1e-209 NADH oxidase K00356; Psort location: Cytoplasmic, score: 9.67. | Ribosomal protein L31; Binds the 23S rRNA. | 0.813 |
| EKY26139.1 | EKY22283.1 | HMPREF0216_02178 | HMPREF0216_03327 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | Pyruvate kinase; KEGG: cbe:Cbei_0485 5.0e-182 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50. | 0.824 |
| EKY26139.1 | EKY27727.1 | HMPREF0216_02178 | HMPREF0216_01201 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | Pyruvate kinase; KEGG: cbe:Cbei_4851 1.2e-187 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | 0.833 |
| EKY26139.1 | EKY28433.1 | HMPREF0216_02178 | HMPREF0216_00784 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.788 |