| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22114.1 | EKY26137.1 | HMPREF0216_03444 | HMPREF0216_02176 | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.428 |
| EKY22114.1 | EKY28433.1 | HMPREF0216_03444 | HMPREF0216_00784 | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.590 |
| EKY22114.1 | EKY28434.1 | HMPREF0216_03444 | HMPREF0216_00785 | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | Riboflavin synthase, alpha subunit. | 0.813 |
| EKY22114.1 | ribBA | HMPREF0216_03444 | HMPREF0216_00786 | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.898 |
| EKY23482.1 | EKY26137.1 | HMPREF0216_02918 | HMPREF0216_02176 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.504 |
| EKY23482.1 | EKY26629.1 | HMPREF0216_02918 | HMPREF0216_01814 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | Putative serine/threonine-protein kinase PrkC. | 0.487 |
| EKY23482.1 | EKY28433.1 | HMPREF0216_02918 | HMPREF0216_00784 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.689 |
| EKY23482.1 | EKY29047.1 | HMPREF0216_02918 | HMPREF0216_00406 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | Type VII secretion protein EssC; KEGG: eci:UTI89_C0905 3.2e-12 ftsK; DNA translocase FtsK K03466; Psort location: CytoplasmicMembrane, score: 8.78. | 0.942 |
| EKY23482.1 | ribBA | HMPREF0216_02918 | HMPREF0216_00786 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.919 |
| EKY23482.1 | ribH | HMPREF0216_02918 | HMPREF0216_00787 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.467 |
| EKY23482.1 | rpsB | HMPREF0216_02918 | HMPREF0216_01722 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.457 |
| EKY26137.1 | EKY22114.1 | HMPREF0216_02176 | HMPREF0216_03444 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753. | 0.428 |
| EKY26137.1 | EKY23482.1 | HMPREF0216_02176 | HMPREF0216_02918 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | 0.504 |
| EKY26137.1 | EKY26629.1 | HMPREF0216_02176 | HMPREF0216_01814 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative serine/threonine-protein kinase PrkC. | 0.492 |
| EKY26137.1 | EKY28433.1 | HMPREF0216_02176 | HMPREF0216_00784 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.928 |
| EKY26137.1 | EKY28434.1 | HMPREF0216_02176 | HMPREF0216_00785 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin synthase, alpha subunit. | 0.499 |
| EKY26137.1 | ribBA | HMPREF0216_02176 | HMPREF0216_00786 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.976 |
| EKY26137.1 | ribH | HMPREF0216_02176 | HMPREF0216_00787 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.554 |
| EKY26629.1 | EKY23482.1 | HMPREF0216_01814 | HMPREF0216_02918 | Putative serine/threonine-protein kinase PrkC. | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | 0.487 |
| EKY26629.1 | EKY26137.1 | HMPREF0216_01814 | HMPREF0216_02176 | Putative serine/threonine-protein kinase PrkC. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.492 |