Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
EKY28457.1Iron-only hydrogenase maturation rSAM protein HydG; KEGG: hor:Hore_19320 8.0e-120 thiH; thiamine biosynthesis protein ThiH K03150; Psort location: Cytoplasmic, score: 7.50. (463 aa)    
Predicted Functional Partners:
EKY28458.1
Hydrogenase maturation GTPase HydF; KEGG: fta:FTA_1243 1.7e-12 trmE; tRNA modification GTPase TrmE K03650; Psort location: Cytoplasmic, score: 9.97.
  
 0.990
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.937
EKY28455.1
Putative iron-only hydrogenase system regulator.
 
     0.914
EKY28456.1
Iron-only hydrogenase maturation rSAM protein HydE; KEGG: cno:NT01CX_1484 1.1e-127 biotin synthase K01012; Psort location: Cytoplasmic, score: 7.50.
 
  
0.859
EKY27732.1
Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
    
 0.662
EKY29105.1
Hypothetical protein.
   
    0.619
EKY28059.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
   
    0.619
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
   
    0.619
EKY28750.1
4Fe-4S binding domain protein; KEGG: cpr:CPR_0261 9.0e-144 hydrogenase subunit (ferredoxin) K00532; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.600
EKY26446.1
FAD dependent oxidoreductase; KEGG: ctc:CTC00417 9.5e-101 oxidoreductase K00100; Psort location: Cytoplasmic, score: 7.50.
    
 0.597
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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