Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKY28462.1tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (343 aa)    
Predicted Functional Partners:
EKY28464.1
Biotin protein ligase domain protein; KEGG: cpf:CPF_0664 4.0e-31 birA; BirA bifunctional protein K03524.
  
    0.642
EKY28465.1
Putative biotin operon repressor; KEGG: cpf:CPF_0664 2.9e-44 birA; BirA bifunctional protein K03524; Psort location: Cytoplasmic, score: 9.97.
  
    0.642
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
    0.620
EKY28463.1
BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00.
       0.593
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
   
  
 0.464
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
   
 
 0.410
EKY23480.1
KEGG: cpe:CPE0991 4.6e-85 truA; tRNA pseudouridine synthase A K06173; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.410
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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