| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY28456.1 | EKY28463.1 | HMPREF0216_00807 | HMPREF0216_00814 | Iron-only hydrogenase maturation rSAM protein HydE; KEGG: cno:NT01CX_1484 1.1e-127 biotin synthase K01012; Psort location: Cytoplasmic, score: 7.50. | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | 0.582 |
| EKY28456.1 | EKY28464.1 | HMPREF0216_00807 | HMPREF0216_00815 | Iron-only hydrogenase maturation rSAM protein HydE; KEGG: cno:NT01CX_1484 1.1e-127 biotin synthase K01012; Psort location: Cytoplasmic, score: 7.50. | Biotin protein ligase domain protein; KEGG: cpf:CPF_0664 4.0e-31 birA; BirA bifunctional protein K03524. | 0.908 |
| EKY28456.1 | EKY28465.1 | HMPREF0216_00807 | HMPREF0216_00816 | Iron-only hydrogenase maturation rSAM protein HydE; KEGG: cno:NT01CX_1484 1.1e-127 biotin synthase K01012; Psort location: Cytoplasmic, score: 7.50. | Putative biotin operon repressor; KEGG: cpf:CPF_0664 2.9e-44 birA; BirA bifunctional protein K03524; Psort location: Cytoplasmic, score: 9.97. | 0.908 |
| EKY28462.1 | EKY28463.1 | HMPREF0216_00813 | HMPREF0216_00814 | tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | 0.594 |
| EKY28462.1 | EKY28464.1 | HMPREF0216_00813 | HMPREF0216_00815 | tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Biotin protein ligase domain protein; KEGG: cpf:CPF_0664 4.0e-31 birA; BirA bifunctional protein K03524. | 0.627 |
| EKY28462.1 | EKY28465.1 | HMPREF0216_00813 | HMPREF0216_00816 | tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Putative biotin operon repressor; KEGG: cpf:CPF_0664 2.9e-44 birA; BirA bifunctional protein K03524; Psort location: Cytoplasmic, score: 9.97. | 0.627 |
| EKY28463.1 | EKY28456.1 | HMPREF0216_00814 | HMPREF0216_00807 | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | Iron-only hydrogenase maturation rSAM protein HydE; KEGG: cno:NT01CX_1484 1.1e-127 biotin synthase K01012; Psort location: Cytoplasmic, score: 7.50. | 0.582 |
| EKY28463.1 | EKY28462.1 | HMPREF0216_00814 | HMPREF0216_00813 | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.594 |
| EKY28463.1 | EKY28464.1 | HMPREF0216_00814 | HMPREF0216_00815 | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | Biotin protein ligase domain protein; KEGG: cpf:CPF_0664 4.0e-31 birA; BirA bifunctional protein K03524. | 0.913 |
| EKY28463.1 | EKY28465.1 | HMPREF0216_00814 | HMPREF0216_00816 | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | Putative biotin operon repressor; KEGG: cpf:CPF_0664 2.9e-44 birA; BirA bifunctional protein K03524; Psort location: Cytoplasmic, score: 9.97. | 0.912 |
| EKY28463.1 | EKY28466.1 | HMPREF0216_00814 | HMPREF0216_00817 | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.488 |
| EKY28463.1 | EKY28697.1 | HMPREF0216_00814 | HMPREF0216_00619 | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | Cobalt transport protein; KEGG: ljf:FI9785_1499 5.5e-73 ABC-type transport system, permease component K02008; Psort location: CytoplasmicMembrane, score: 10.00. | 0.971 |
| EKY28463.1 | cbiA | HMPREF0216_00814 | HMPREF0216_03179 | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.536 |
| EKY28463.1 | ecfA | HMPREF0216_00814 | HMPREF0216_01185 | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | Cobalt ABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | 0.975 |
| EKY28463.1 | ecfA-2 | HMPREF0216_00814 | HMPREF0216_01186 | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | ABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | 0.975 |
| EKY28463.1 | ecfT | HMPREF0216_00814 | HMPREF0216_01187 | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | Cobalt transport protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | 0.984 |
| EKY28464.1 | EKY28456.1 | HMPREF0216_00815 | HMPREF0216_00807 | Biotin protein ligase domain protein; KEGG: cpf:CPF_0664 4.0e-31 birA; BirA bifunctional protein K03524. | Iron-only hydrogenase maturation rSAM protein HydE; KEGG: cno:NT01CX_1484 1.1e-127 biotin synthase K01012; Psort location: Cytoplasmic, score: 7.50. | 0.908 |
| EKY28464.1 | EKY28462.1 | HMPREF0216_00815 | HMPREF0216_00813 | Biotin protein ligase domain protein; KEGG: cpf:CPF_0664 4.0e-31 birA; BirA bifunctional protein K03524. | tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.627 |
| EKY28464.1 | EKY28463.1 | HMPREF0216_00815 | HMPREF0216_00814 | Biotin protein ligase domain protein; KEGG: cpf:CPF_0664 4.0e-31 birA; BirA bifunctional protein K03524. | BioY family protein; KEGG: acl:ACL_0466 3.7e-19 birA; biotin-[acetyl-CoA-carboxylase] ligase K03523; Psort location: CytoplasmicMembrane, score: 10.00. | 0.913 |
| EKY28464.1 | EKY28465.1 | HMPREF0216_00815 | HMPREF0216_00816 | Biotin protein ligase domain protein; KEGG: cpf:CPF_0664 4.0e-31 birA; BirA bifunctional protein K03524. | Putative biotin operon repressor; KEGG: cpf:CPF_0664 2.9e-44 birA; BirA bifunctional protein K03524; Psort location: Cytoplasmic, score: 9.97. | 0.999 |