Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKY28331.1Ribose-phosphate diphosphokinase; KEGG: cpr:CPR_1519 2.5e-164 prs; phosphoribosylpyrophosphate synthetase K00948; Psort location: Cytoplasmic, score: 9.97; Belongs to the ribose-phosphate pyrophosphokinase family. (363 aa)    
Predicted Functional Partners:
EKY26443.1
KEGG: cbt:CLH_0670 9.2e-261 NADH oxidase; Psort location: Cytoplasmic, score: 7.50.
  
 0.917
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
     
 
0.900
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
  
 
 0.840
EKY27654.1
Ribose-5-phosphate isomerase B; KEGG: cbe:Cbei_0407 2.2e-60 RpiB/LacA/LacB family sugar-phosphate isomerase K01808; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.837
EKY22133.1
Phosphoglucomutase; KEGG: cpr:CPR_1841 9.9e-225 phosphomannomutase K01840; Psort location: Cytoplasmic, score: 7.50.
  
 0.837
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.836
EKY26358.1
KEGG: cbe:Cbei_0761 2.1e-64 ribose 5-phosphate isomerase K01807; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.832
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.832
EKY26463.1
Hypothetical protein; KEGG: cpf:CPF_1884 1.9e-31 rbsK; ribokinase K00852; Psort location: Cytoplasmic, score: 9.97.
   
 0.817
EKY26464.1
Putative ribokinase; KEGG: cpe:CPE1632 5.0e-79 rbsK; ribokinase; K00852 ribokinase; Psort location: Cytoplasmic, score: 9.97; Belongs to the carbohydrate kinase PfkB family.
   
 0.817
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
Server load: low (18%) [HD]