Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (356 aa)    
Predicted Functional Partners:
EKY28135.1
Hypothetical protein; KEGG: ddf:DEFDS_0730 1.0e-15 monogalactosyldiacylglycerol synthase.
 
   
 0.863
EKY28134.1
Polysaccharide deacetylase; KEGG: bha:BH1917 2.3e-28 notB; chitooligosaccharide deacetylase K01463; Psort location: Extracellular, score: 9.60.
 
  
 0.851
EKY28136.1
Monogalactosyldiacylglycerol synthase protein; KEGG: cbl:CLK_3302 4.1e-29 hypothetical protein; K03429 1,2-diacylglycerol 3-glucosyltransferase.
 
   
 0.825
EKY23482.1
Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.615
EKY27753.1
Hypothetical protein; KEGG: bab:bbp155 0.0021 nuoN; NADH dehydrogenase subunit 2 K00343; Psort location: CytoplasmicMembrane, score: 10.00.
    
  0.489
EKY25756.1
[2Fe-2S]-binding domain protein.
  
     0.484
EKY28132.1
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
       0.482
msrA
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.433
EKY27156.1
KEGG: cbk:CLL_A1286 1.7e-71 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.430
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
       0.413
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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