Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKY27925.1Homocitrate synthase; KEGG: cbe:Cbei_0069 1.5e-166 aksA; trans-homoaconitate synthase; K01655 homocitrate synthase K02594; Psort location: Cytoplasmic, score: 7.50; Belongs to the alpha-IPM synthase/homocitrate synthase family. (386 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
 
 0.947
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.945
EKY28532.1
KEGG: cbk:CLL_A0326 5.0e-214 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652; Psort location: Cytoplasmic, score: 9.95.
 
 
 0.927
ilvD
KEGG: ccb:Clocel_1323 4.9e-223 dihydroxy-acid dehydratase K01687; Psort location: Cytoplasmic, score: 7.50; Belongs to the IlvD/Edd family.
 
 
 0.918
EKY28538.1
KEGG: cbe:Cbei_0212 6.6e-61 acetolactate synthase, small subunit; K01653 acetolactate synthase I/III small subunit; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.911
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.896
EKY23227.1
Branched-chain-amino-acid transaminase; KEGG: ckl:CKL_3620 3.3e-146 ilvE3; branched-chain amino acid aminotransferase K00826; Psort location: Cytoplasmic, score: 7.50.
  
 0.890
EKY22089.1
acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.882
EKY29465.1
Pyruvate synthase; KEGG: cbt:CLH_0756 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.880
EKY29370.1
Hypothetical protein; KEGG: cbk:CLL_A0790 9.0e-128 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737.
  
 
 0.880
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.