Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKY27642.1Stage II sporulation protein R; Psort location: Cytoplasmic, score: 7.50. (212 aa)    
Predicted Functional Partners:
EKY22752.1
Stage II sporulation protein P.
  
   
 0.862
EKY25257.1
KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00.
  
   
 0.857
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.857
EKY27672.1
Sporulation transcriptional regulator SpoIIID; Psort location: Cytoplasmic, score: 7.50.
  
   
 0.856
EKY26988.1
Stage III sporulation protein AA; KEGG: rso:RSc1335 0.0072 clpB; ATP-dependent protease K03695; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.839
EKY27009.1
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.835
EKY27243.1
Stage V sporulation protein T; Psort location: Cytoplasmic, score: 9.97.
  
   
 0.834
EKY26645.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.834
EKY26660.1
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.811
EKY22730.1
Sporulation protein YqfD; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.811
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
Server load: medium (74%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.