| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22725.1 | EKY26172.1 | HMPREF0216_03089 | HMPREF0216_02211 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 5'-nucleotidase protein. | 0.559 |
| EKY22725.1 | EKY26192.1 | HMPREF0216_03089 | HMPREF0216_02231 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | 0.814 |
| EKY22725.1 | EKY27027.1 | HMPREF0216_03089 | HMPREF0216_01630 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | KEGG: cpe:CPE1807 7.0e-160 deoA; pyrimidine-nucleoside phosphorylase; K00756 pyrimidine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 7.50. | 0.951 |
| EKY22725.1 | tdk | HMPREF0216_03089 | HMPREF0216_01292 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine kinase; KEGG: cbt:CLH_0472 8.2e-79 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 7.50. | 0.908 |
| EKY26172.1 | EKY22725.1 | HMPREF0216_02211 | HMPREF0216_03089 | 5'-nucleotidase protein. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.559 |
| EKY26172.1 | EKY26192.1 | HMPREF0216_02211 | HMPREF0216_02231 | 5'-nucleotidase protein. | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | 0.828 |
| EKY26172.1 | EKY26364.1 | HMPREF0216_02211 | HMPREF0216_02005 | 5'-nucleotidase protein. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.559 |
| EKY26172.1 | EKY27027.1 | HMPREF0216_02211 | HMPREF0216_01630 | 5'-nucleotidase protein. | KEGG: cpe:CPE1807 7.0e-160 deoA; pyrimidine-nucleoside phosphorylase; K00756 pyrimidine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 7.50. | 0.774 |
| EKY26172.1 | EKY27656.1 | HMPREF0216_02211 | HMPREF0216_01299 | 5'-nucleotidase protein. | KEGG: cpr:CPR_1134 1.4e-58 cytidine/deoxycytidylate deaminase family protein; K01493 dCMP deaminase; Psort location: Cytoplasmic, score: 7.50. | 0.773 |
| EKY26172.1 | dut | HMPREF0216_02211 | HMPREF0216_01409 | 5'-nucleotidase protein. | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.767 |
| EKY26172.1 | tdk | HMPREF0216_02211 | HMPREF0216_01292 | 5'-nucleotidase protein. | Thymidine kinase; KEGG: cbt:CLH_0472 8.2e-79 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 7.50. | 0.796 |
| EKY26172.1 | thyA | HMPREF0216_02211 | HMPREF0216_00285 | 5'-nucleotidase protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.771 |
| EKY26192.1 | EKY22725.1 | HMPREF0216_02231 | HMPREF0216_03089 | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.814 |
| EKY26192.1 | EKY26172.1 | HMPREF0216_02231 | HMPREF0216_02211 | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase protein. | 0.828 |
| EKY26192.1 | EKY26364.1 | HMPREF0216_02231 | HMPREF0216_02005 | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.786 |
| EKY26192.1 | EKY27027.1 | HMPREF0216_02231 | HMPREF0216_01630 | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | KEGG: cpe:CPE1807 7.0e-160 deoA; pyrimidine-nucleoside phosphorylase; K00756 pyrimidine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 7.50. | 0.809 |
| EKY26192.1 | EKY27656.1 | HMPREF0216_02231 | HMPREF0216_01299 | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | KEGG: cpr:CPR_1134 1.4e-58 cytidine/deoxycytidylate deaminase family protein; K01493 dCMP deaminase; Psort location: Cytoplasmic, score: 7.50. | 0.795 |
| EKY26192.1 | dut | HMPREF0216_02231 | HMPREF0216_01409 | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.793 |
| EKY26192.1 | tdk | HMPREF0216_02231 | HMPREF0216_01292 | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | Thymidine kinase; KEGG: cbt:CLH_0472 8.2e-79 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 7.50. | 0.807 |
| EKY26192.1 | thyA | HMPREF0216_02231 | HMPREF0216_00285 | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.825 |