| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY25379.1 | EKY25396.1 | HMPREF0216_02478 | HMPREF0216_02495 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | 0.999 |
| EKY25379.1 | EKY26110.1 | HMPREF0216_02478 | HMPREF0216_02149 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.911 |
| EKY25379.1 | EKY26627.1 | HMPREF0216_02478 | HMPREF0216_01812 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.796 |
| EKY25379.1 | EKY27654.1 | HMPREF0216_02478 | HMPREF0216_01297 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Ribose-5-phosphate isomerase B; KEGG: cbe:Cbei_0407 2.2e-60 RpiB/LacA/LacB family sugar-phosphate isomerase K01808; Psort location: Cytoplasmic, score: 7.50. | 0.879 |
| EKY25379.1 | EKY29370.1 | HMPREF0216_02478 | HMPREF0216_00231 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Hypothetical protein; KEGG: cbk:CLL_A0790 9.0e-128 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | 0.999 |
| EKY25379.1 | EKY29465.1 | HMPREF0216_02478 | HMPREF0216_00230 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Pyruvate synthase; KEGG: cbt:CLH_0756 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737; Psort location: Cytoplasmic, score: 7.50. | 0.999 |
| EKY25379.1 | deoC | HMPREF0216_02478 | HMPREF0216_03139 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.824 |
| EKY25379.1 | glyA | HMPREF0216_02478 | HMPREF0216_02267 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.525 |
| EKY25396.1 | EKY25379.1 | HMPREF0216_02495 | HMPREF0216_02478 | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | 0.999 |
| EKY25396.1 | EKY26110.1 | HMPREF0216_02495 | HMPREF0216_02149 | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.911 |
| EKY25396.1 | EKY26627.1 | HMPREF0216_02495 | HMPREF0216_01812 | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.796 |
| EKY25396.1 | EKY27654.1 | HMPREF0216_02495 | HMPREF0216_01297 | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | Ribose-5-phosphate isomerase B; KEGG: cbe:Cbei_0407 2.2e-60 RpiB/LacA/LacB family sugar-phosphate isomerase K01808; Psort location: Cytoplasmic, score: 7.50. | 0.879 |
| EKY25396.1 | EKY29370.1 | HMPREF0216_02495 | HMPREF0216_00231 | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | Hypothetical protein; KEGG: cbk:CLL_A0790 9.0e-128 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | 0.999 |
| EKY25396.1 | EKY29465.1 | HMPREF0216_02495 | HMPREF0216_00230 | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | Pyruvate synthase; KEGG: cbt:CLH_0756 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737; Psort location: Cytoplasmic, score: 7.50. | 0.999 |
| EKY25396.1 | deoC | HMPREF0216_02495 | HMPREF0216_03139 | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.824 |
| EKY25396.1 | glyA | HMPREF0216_02495 | HMPREF0216_02267 | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.525 |
| EKY26110.1 | EKY25379.1 | HMPREF0216_02149 | HMPREF0216_02478 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | 0.911 |
| EKY26110.1 | EKY25396.1 | HMPREF0216_02149 | HMPREF0216_02495 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | 0.911 |
| EKY26110.1 | EKY27654.1 | HMPREF0216_02149 | HMPREF0216_01297 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Ribose-5-phosphate isomerase B; KEGG: cbe:Cbei_0407 2.2e-60 RpiB/LacA/LacB family sugar-phosphate isomerase K01808; Psort location: Cytoplasmic, score: 7.50. | 0.841 |
| EKY26110.1 | EKY29370.1 | HMPREF0216_02149 | HMPREF0216_00231 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: cbk:CLL_A0790 9.0e-128 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | 0.874 |