Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKY27656.1KEGG: cpr:CPR_1134 1.4e-58 cytidine/deoxycytidylate deaminase family protein; K01493 dCMP deaminase; Psort location: Cytoplasmic, score: 7.50. (165 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.922
dut
Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 0.869
tdk
Thymidine kinase; KEGG: cbt:CLH_0472 8.2e-79 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.860
EKY24034.1
S1 RNA binding domain protein.
    
  0.838
EKY26258.1
Deoxynucleoside kinase; KEGG: cbt:CLH_1831 2.0e-84 deoxyguanosIne kinase; Psort location: Cytoplasmic, score: 7.50.
   
 0.809
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
  0.802
EKY22284.1
Putative 30S ribosomal protein S1; KEGG: dau:Daud_1178 6.3e-72 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein; K02945 small subunit ribosomal protein S1; K03527 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Psort location: Cytoplasmic, score: 9.97.
    
  0.802
EKY26192.1
LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family.
  
 
  0.795
cmk
Cytidylate kinase.
    
  0.795
EKY26172.1
5'-nucleotidase protein.
  
 
  0.773
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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