| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY27668.1 | murA-2 | HMPREF0216_01311 | HMPREF0216_01312 | Hypothetical protein; KEGG: rbe:RBE_0092 0.0023 atpH; F0F1 ATP synthase subunit delta K02113. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.819 |
| EKY29031.1 | EKY29497.1 | HMPREF0216_00390 | HMPREF0216_00204 | Putative epimerase/dehydratase WbiI; KEGG: cbt:CLH_2929 1.2e-173 Cap5D; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: aoe:Clos_2569 2.5e-123 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | 0.873 |
| EKY29031.1 | glmU | HMPREF0216_00390 | HMPREF0216_00021 | Putative epimerase/dehydratase WbiI; KEGG: cbt:CLH_2929 1.2e-173 Cap5D; Psort location: CytoplasmicMembrane, score: 10.00. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.831 |
| EKY29031.1 | murA | HMPREF0216_00390 | HMPREF0216_01121 | Putative epimerase/dehydratase WbiI; KEGG: cbt:CLH_2929 1.2e-173 Cap5D; Psort location: CytoplasmicMembrane, score: 10.00. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.813 |
| EKY29031.1 | murA-2 | HMPREF0216_00390 | HMPREF0216_01312 | Putative epimerase/dehydratase WbiI; KEGG: cbt:CLH_2929 1.2e-173 Cap5D; Psort location: CytoplasmicMembrane, score: 10.00. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.813 |
| EKY29497.1 | EKY29031.1 | HMPREF0216_00204 | HMPREF0216_00390 | KEGG: aoe:Clos_2569 2.5e-123 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | Putative epimerase/dehydratase WbiI; KEGG: cbt:CLH_2929 1.2e-173 Cap5D; Psort location: CytoplasmicMembrane, score: 10.00. | 0.873 |
| EKY29497.1 | glmU | HMPREF0216_00204 | HMPREF0216_00021 | KEGG: aoe:Clos_2569 2.5e-123 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.859 |
| EKY29497.1 | mraY | HMPREF0216_00204 | HMPREF0216_01563 | KEGG: aoe:Clos_2569 2.5e-123 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.638 |
| EKY29497.1 | murA | HMPREF0216_00204 | HMPREF0216_01121 | KEGG: aoe:Clos_2569 2.5e-123 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.825 |
| EKY29497.1 | murA-2 | HMPREF0216_00204 | HMPREF0216_01312 | KEGG: aoe:Clos_2569 2.5e-123 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.825 |
| glmU | EKY29031.1 | HMPREF0216_00021 | HMPREF0216_00390 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Putative epimerase/dehydratase WbiI; KEGG: cbt:CLH_2929 1.2e-173 Cap5D; Psort location: CytoplasmicMembrane, score: 10.00. | 0.831 |
| glmU | EKY29497.1 | HMPREF0216_00021 | HMPREF0216_00204 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | KEGG: aoe:Clos_2569 2.5e-123 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | 0.859 |
| glmU | mraY | HMPREF0216_00021 | HMPREF0216_01563 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.566 |
| glmU | murA | HMPREF0216_00021 | HMPREF0216_01121 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.948 |
| glmU | murA-2 | HMPREF0216_00021 | HMPREF0216_01312 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.950 |
| glmU | murC | HMPREF0216_00021 | HMPREF0216_01507 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.757 |
| glmU | murE | HMPREF0216_00021 | HMPREF0216_01561 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.806 |
| glmU | murF | HMPREF0216_00021 | HMPREF0216_01562 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.606 |
| mraY | EKY29497.1 | HMPREF0216_01563 | HMPREF0216_00204 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | KEGG: aoe:Clos_2569 2.5e-123 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | 0.638 |
| mraY | glmU | HMPREF0216_01563 | HMPREF0216_00021 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.566 |