| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY23257.1 | EKY26296.1 | HMPREF0216_03042 | HMPREF0216_02078 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative glycerate dehydrogenase; KEGG: cbk:CLL_A0984 3.9e-111 2-hydroxyacid dehydrogenase; Psort location: Cytoplasmic, score: 9.67; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.811 |
| EKY23257.1 | EKY27412.1 | HMPREF0216_03042 | HMPREF0216_01445 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Transcriptional regulator, GntR family. | 0.685 |
| EKY23257.1 | EKY27746.1 | HMPREF0216_03042 | HMPREF0216_01220 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | KEGG: cpe:CPE0150 2.1e-96 2-dehydro-3-deoxyphosphogluconate/4-hydroxy-2-ox oglutarate aldolase; K01625 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase; Psort location: Cytoplasmic, score: 9.97. | 0.773 |
| EKY23257.1 | EKY28426.1 | HMPREF0216_03042 | HMPREF0216_00777 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Class II glutamine amidotransferase. | 0.896 |
| EKY23257.1 | EKY29328.1 | HMPREF0216_03042 | HMPREF0216_00296 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aminotransferase, class V; KEGG: cpr:CPR_0063 6.6e-148 aminotransferase, class V; K00839 aminotransferase; Psort location: Cytoplasmic, score: 9.97. | 0.878 |
| EKY23257.1 | EKY29329.1 | HMPREF0216_03042 | HMPREF0216_00297 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | KEGG: cbt:CLH_3217 2.5e-109 D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.868 |
| EKY23257.1 | glyA | HMPREF0216_03042 | HMPREF0216_02267 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.813 |
| EKY26296.1 | EKY23257.1 | HMPREF0216_02078 | HMPREF0216_03042 | Putative glycerate dehydrogenase; KEGG: cbk:CLL_A0984 3.9e-111 2-hydroxyacid dehydrogenase; Psort location: Cytoplasmic, score: 9.67; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.811 |
| EKY26296.1 | EKY27412.1 | HMPREF0216_02078 | HMPREF0216_01445 | Putative glycerate dehydrogenase; KEGG: cbk:CLL_A0984 3.9e-111 2-hydroxyacid dehydrogenase; Psort location: Cytoplasmic, score: 9.67; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Transcriptional regulator, GntR family. | 0.767 |
| EKY26296.1 | EKY27746.1 | HMPREF0216_02078 | HMPREF0216_01220 | Putative glycerate dehydrogenase; KEGG: cbk:CLL_A0984 3.9e-111 2-hydroxyacid dehydrogenase; Psort location: Cytoplasmic, score: 9.67; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | KEGG: cpe:CPE0150 2.1e-96 2-dehydro-3-deoxyphosphogluconate/4-hydroxy-2-ox oglutarate aldolase; K01625 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase; Psort location: Cytoplasmic, score: 9.97. | 0.805 |
| EKY26296.1 | EKY29328.1 | HMPREF0216_02078 | HMPREF0216_00296 | Putative glycerate dehydrogenase; KEGG: cbk:CLL_A0984 3.9e-111 2-hydroxyacid dehydrogenase; Psort location: Cytoplasmic, score: 9.67; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Aminotransferase, class V; KEGG: cpr:CPR_0063 6.6e-148 aminotransferase, class V; K00839 aminotransferase; Psort location: Cytoplasmic, score: 9.97. | 0.820 |
| EKY26296.1 | EKY29329.1 | HMPREF0216_02078 | HMPREF0216_00297 | Putative glycerate dehydrogenase; KEGG: cbk:CLL_A0984 3.9e-111 2-hydroxyacid dehydrogenase; Psort location: Cytoplasmic, score: 9.67; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | KEGG: cbt:CLH_3217 2.5e-109 D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.823 |
| EKY26296.1 | dapA | HMPREF0216_02078 | HMPREF0216_02750 | Putative glycerate dehydrogenase; KEGG: cbk:CLL_A0984 3.9e-111 2-hydroxyacid dehydrogenase; Psort location: Cytoplasmic, score: 9.67; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.786 |
| EKY26428.1 | EKY27412.1 | HMPREF0216_01924 | HMPREF0216_01445 | Chorismate mutase; KEGG: cbe:Cbei_4573 1.1e-122 chorismate mutase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97. | Transcriptional regulator, GntR family. | 0.841 |
| EKY26428.1 | EKY28426.1 | HMPREF0216_01924 | HMPREF0216_00777 | Chorismate mutase; KEGG: cbe:Cbei_4573 1.1e-122 chorismate mutase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97. | Class II glutamine amidotransferase. | 0.733 |
| EKY26428.1 | EKY29329.1 | HMPREF0216_01924 | HMPREF0216_00297 | Chorismate mutase; KEGG: cbe:Cbei_4573 1.1e-122 chorismate mutase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97. | KEGG: cbt:CLH_3217 2.5e-109 D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.613 |
| EKY26428.1 | dapA | HMPREF0216_01924 | HMPREF0216_02750 | Chorismate mutase; KEGG: cbe:Cbei_4573 1.1e-122 chorismate mutase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.742 |
| EKY26428.1 | glyA | HMPREF0216_01924 | HMPREF0216_02267 | Chorismate mutase; KEGG: cbe:Cbei_4573 1.1e-122 chorismate mutase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.487 |
| EKY27412.1 | EKY23257.1 | HMPREF0216_01445 | HMPREF0216_03042 | Transcriptional regulator, GntR family. | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.685 |
| EKY27412.1 | EKY26296.1 | HMPREF0216_01445 | HMPREF0216_02078 | Transcriptional regulator, GntR family. | Putative glycerate dehydrogenase; KEGG: cbk:CLL_A0984 3.9e-111 2-hydroxyacid dehydrogenase; Psort location: Cytoplasmic, score: 9.67; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.767 |