STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (405 aa)    
Predicted Functional Partners:
pgi
KEGG: cbk:CLL_A0403 4.0e-196 pgi; glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family.
  
 0.980
EKY27727.1
Pyruvate kinase; KEGG: cbe:Cbei_4851 1.2e-187 pyruvate kinase K00873; Belongs to the pyruvate kinase family.
  
 
 0.979
EKY26139.1
Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family.
  
 
 0.979
EKY22283.1
Pyruvate kinase; KEGG: cbe:Cbei_0485 5.0e-182 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.979
EKY28731.1
Class II aldolase, tagatose bisphosphate family; KEGG: cdf:CD3074 1.3e-117 gatY; tagatose-bisphosphate aldolase K08302; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.936
EKY27654.1
Ribose-5-phosphate isomerase B; KEGG: cbe:Cbei_0407 2.2e-60 RpiB/LacA/LacB family sugar-phosphate isomerase K01808; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.890
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
   
  
 0.882
EKY28189.1
Fructose-1,6-bisphosphate aldolase, class II.
  
 
 0.878
pfkA-2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
  
0.862
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
0.852
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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