| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY26091.1 | EKY26434.1 | HMPREF0216_02130 | HMPREF0216_01930 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Adenylate cyclase; KEGG: cbe:Cbei_4540 1.5e-63 adenylate cyclase; K05873 adenylate cyclase, class 2; Psort location: Cytoplasmic, score: 7.50. | 0.656 |
| EKY26091.1 | EKY27308.1 | HMPREF0216_02130 | HMPREF0216_01472 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Hypothetical protein. | 0.535 |
| EKY26091.1 | EKY29793.1 | HMPREF0216_02130 | HMPREF0216_00037 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | DNA-binding helix-turn-helix protein; KEGG: eba:ebA2762 0.0030 boxR; anaerobic benzoate catabolism transcriptional regulator; K00891 shikimate kinase; Psort location: Cytoplasmic, score: 7.50. | 0.436 |
| EKY26434.1 | EKY26091.1 | HMPREF0216_01930 | HMPREF0216_02130 | Adenylate cyclase; KEGG: cbe:Cbei_4540 1.5e-63 adenylate cyclase; K05873 adenylate cyclase, class 2; Psort location: Cytoplasmic, score: 7.50. | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.656 |
| EKY26434.1 | EKY27308.1 | HMPREF0216_01930 | HMPREF0216_01472 | Adenylate cyclase; KEGG: cbe:Cbei_4540 1.5e-63 adenylate cyclase; K05873 adenylate cyclase, class 2; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein. | 0.516 |
| EKY26434.1 | EKY28132.1 | HMPREF0216_01930 | HMPREF0216_00975 | Adenylate cyclase; KEGG: cbe:Cbei_4540 1.5e-63 adenylate cyclase; K05873 adenylate cyclase, class 2; Psort location: Cytoplasmic, score: 7.50. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.763 |
| EKY26434.1 | EKY29793.1 | HMPREF0216_01930 | HMPREF0216_00037 | Adenylate cyclase; KEGG: cbe:Cbei_4540 1.5e-63 adenylate cyclase; K05873 adenylate cyclase, class 2; Psort location: Cytoplasmic, score: 7.50. | DNA-binding helix-turn-helix protein; KEGG: eba:ebA2762 0.0030 boxR; anaerobic benzoate catabolism transcriptional regulator; K00891 shikimate kinase; Psort location: Cytoplasmic, score: 7.50. | 0.505 |
| EKY26662.1 | EKY27308.1 | HMPREF0216_01847 | HMPREF0216_01472 | sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Hypothetical protein. | 0.506 |
| EKY27305.1 | EKY27306.1 | HMPREF0216_01469 | HMPREF0216_01470 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | S4 domain protein YaaA; KEGG: bpi:BPLAN_550 0.00035 hypothetical protein; K06178 ribosomal large subunit pseudouridine synthase B. | 0.824 |
| EKY27305.1 | EKY27308.1 | HMPREF0216_01469 | HMPREF0216_01472 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein. | 0.647 |
| EKY27305.1 | gyrA | HMPREF0216_01469 | HMPREF0216_01474 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.738 |
| EKY27305.1 | gyrB | HMPREF0216_01469 | HMPREF0216_01473 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.870 |
| EKY27305.1 | recF | HMPREF0216_01469 | HMPREF0216_01471 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.935 |
| EKY27306.1 | EKY27305.1 | HMPREF0216_01470 | HMPREF0216_01469 | S4 domain protein YaaA; KEGG: bpi:BPLAN_550 0.00035 hypothetical protein; K06178 ribosomal large subunit pseudouridine synthase B. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.824 |
| EKY27306.1 | EKY27308.1 | HMPREF0216_01470 | HMPREF0216_01472 | S4 domain protein YaaA; KEGG: bpi:BPLAN_550 0.00035 hypothetical protein; K06178 ribosomal large subunit pseudouridine synthase B. | Hypothetical protein. | 0.742 |
| EKY27306.1 | gyrA | HMPREF0216_01470 | HMPREF0216_01474 | S4 domain protein YaaA; KEGG: bpi:BPLAN_550 0.00035 hypothetical protein; K06178 ribosomal large subunit pseudouridine synthase B. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.559 |
| EKY27306.1 | gyrB | HMPREF0216_01470 | HMPREF0216_01473 | S4 domain protein YaaA; KEGG: bpi:BPLAN_550 0.00035 hypothetical protein; K06178 ribosomal large subunit pseudouridine synthase B. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.619 |
| EKY27306.1 | recF | HMPREF0216_01470 | HMPREF0216_01471 | S4 domain protein YaaA; KEGG: bpi:BPLAN_550 0.00035 hypothetical protein; K06178 ribosomal large subunit pseudouridine synthase B. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.876 |
| EKY27308.1 | EKY26091.1 | HMPREF0216_01472 | HMPREF0216_02130 | Hypothetical protein. | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.535 |
| EKY27308.1 | EKY26434.1 | HMPREF0216_01472 | HMPREF0216_01930 | Hypothetical protein. | Adenylate cyclase; KEGG: cbe:Cbei_4540 1.5e-63 adenylate cyclase; K05873 adenylate cyclase, class 2; Psort location: Cytoplasmic, score: 7.50. | 0.516 |