STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
prsRibose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (333 aa)    
Predicted Functional Partners:
EKY26443.1
KEGG: cbt:CLH_0670 9.2e-261 NADH oxidase; Psort location: Cytoplasmic, score: 7.50.
  
 0.945
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
  
 0.872
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 0.862
EKY22133.1
Phosphoglucomutase; KEGG: cpr:CPR_1841 9.9e-225 phosphomannomutase K01840; Psort location: Cytoplasmic, score: 7.50.
  
 0.855
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
  
 
 0.852
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.849
EKY27654.1
Ribose-5-phosphate isomerase B; KEGG: cbe:Cbei_0407 2.2e-60 RpiB/LacA/LacB family sugar-phosphate isomerase K01808; Psort location: Cytoplasmic, score: 7.50.
    
 0.847
EKY26463.1
Hypothetical protein; KEGG: cpf:CPF_1884 1.9e-31 rbsK; ribokinase K00852; Psort location: Cytoplasmic, score: 9.97.
   
 0.847
EKY26464.1
Putative ribokinase; KEGG: cpe:CPE1632 5.0e-79 rbsK; ribokinase; K00852 ribokinase; Psort location: Cytoplasmic, score: 9.97; Belongs to the carbohydrate kinase PfkB family.
   
 0.847
EKY26358.1
KEGG: cbe:Cbei_0761 2.1e-64 ribose 5-phosphate isomerase K01807; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.847
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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