STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EKY27254.1KEGG: bca:BCE_0044 5.9e-60 purR; pur operon repressor K09685; Psort location: Cytoplasmic, score: 9.95. (271 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 0.967
EKY27162.1
Adenylosuccinate lyase; KEGG: cpr:CPR_1640 1.9e-205 purB; adenylosuccinate lyase K01756; Psort location: Cytoplasmic, score: 7.50.
  
 0.919
purH
KEGG: cpe:CPE0686 5.5e-215 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 7.50.
  
 0.890
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
  
 0.883
EKY27256.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.883
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.853
EKY29672.1
Guanylate kinase; KEGG: apl:APL_0256 1.2e-21 gmk; guanylate kinase K00942; Psort location: Cytoplasmic, score: 9.67.
  
 
 0.844
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.844
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
  0.834
ade
Adenine deaminase; KEGG: cbe:Cbei_1277 2.9e-193 adenine deaminase K01486; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.833
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.