| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY27002.1 | folD | HMPREF0216_01605 | HMPREF0216_01602 | Putative geranyltranstransferase; KEGG: cbe:Cbei_1705 8.8e-98 polyprenyl synthetase; K13789 geranylgeranyl diphosphate synthase, type II; Psort location: Cytoplasmic, score: 9.97. | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.881 |
| EKY27002.1 | nusB | HMPREF0216_01605 | HMPREF0216_01601 | Putative geranyltranstransferase; KEGG: cbe:Cbei_1705 8.8e-98 polyprenyl synthetase; K13789 geranylgeranyl diphosphate synthase, type II; Psort location: Cytoplasmic, score: 9.97. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.778 |
| EKY27002.1 | xseA | HMPREF0216_01605 | HMPREF0216_01603 | Putative geranyltranstransferase; KEGG: cbe:Cbei_1705 8.8e-98 polyprenyl synthetase; K13789 geranylgeranyl diphosphate synthase, type II; Psort location: Cytoplasmic, score: 9.97. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.938 |
| EKY27002.1 | xseB | HMPREF0216_01605 | HMPREF0216_01604 | Putative geranyltranstransferase; KEGG: cbe:Cbei_1705 8.8e-98 polyprenyl synthetase; K13789 geranylgeranyl diphosphate synthase, type II; Psort location: Cytoplasmic, score: 9.97. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.926 |
| fmt | folD | HMPREF0216_01819 | HMPREF0216_01602 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.935 |
| fmt | nusB | HMPREF0216_01819 | HMPREF0216_01601 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.786 |
| fmt | nusG | HMPREF0216_01819 | HMPREF0216_01476 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.422 |
| fmt | rpoZ | HMPREF0216_01819 | HMPREF0216_01823 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.729 |
| folD | EKY27002.1 | HMPREF0216_01602 | HMPREF0216_01605 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Putative geranyltranstransferase; KEGG: cbe:Cbei_1705 8.8e-98 polyprenyl synthetase; K13789 geranylgeranyl diphosphate synthase, type II; Psort location: Cytoplasmic, score: 9.97. | 0.881 |
| folD | fmt | HMPREF0216_01602 | HMPREF0216_01819 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.935 |
| folD | nusB | HMPREF0216_01602 | HMPREF0216_01601 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.959 |
| folD | xseA | HMPREF0216_01602 | HMPREF0216_01603 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.910 |
| folD | xseB | HMPREF0216_01602 | HMPREF0216_01604 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.861 |
| nusA | nusB | HMPREF0216_03437 | HMPREF0216_01601 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.841 |
| nusA | nusG | HMPREF0216_03437 | HMPREF0216_01476 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.980 |
| nusA | rpoZ | HMPREF0216_03437 | HMPREF0216_01823 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.934 |
| nusA | rpsJ | HMPREF0216_03437 | HMPREF0216_01150 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.980 |
| nusB | EKY27002.1 | HMPREF0216_01601 | HMPREF0216_01605 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Putative geranyltranstransferase; KEGG: cbe:Cbei_1705 8.8e-98 polyprenyl synthetase; K13789 geranylgeranyl diphosphate synthase, type II; Psort location: Cytoplasmic, score: 9.97. | 0.778 |
| nusB | fmt | HMPREF0216_01601 | HMPREF0216_01819 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.786 |
| nusB | folD | HMPREF0216_01601 | HMPREF0216_01602 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.959 |