STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKInorganic polyphosphate/ATP-NAD kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (276 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.934
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.879
EKY27004.1
Ribosomal RNA large subunit methyltransferase J; KEGG: apb:SAR116_1064 5.2e-45 predicted rRNA methylase K06442; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.859
cobB
Putative NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
 
 0.851
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
    
 0.851
EKY22256.1
Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50.
     
 0.818
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.816
EKY25416.1
Hydrolase, NUDIX family; KEGG: clj:CLJU_c19510 2.0e-59 putative pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50.
     
 0.815
EKY27007.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.783
EKY27002.1
Putative geranyltranstransferase; KEGG: cbe:Cbei_1705 8.8e-98 polyprenyl synthetase; K13789 geranylgeranyl diphosphate synthase, type II; Psort location: Cytoplasmic, score: 9.97.
 
 
   0.780
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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