| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY23236.1 | EKY25829.1 | HMPREF0216_03021 | HMPREF0216_02315 | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.565 |
| EKY23236.1 | EKY25831.1 | HMPREF0216_03021 | HMPREF0216_02317 | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: ere:EUBREC_1922 4.8e-10 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.565 |
| EKY23236.1 | EKY25834.1 | HMPREF0216_03021 | HMPREF0216_02320 | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | KEGG: cpe:CPE1040 7.5e-108 threonine-phosphate decarboxylase K04720. | 0.669 |
| EKY23236.1 | EKY26827.1 | HMPREF0216_03021 | HMPREF0216_01704 | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | Putative cob(I)yrinic acid a,c-diamide adenosyltransferase; KEGG: cbk:CLL_A2924 4.0e-54 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; K00798 cob(I)alamin adenosyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.763 |
| EKY23236.1 | EKY29258.1 | HMPREF0216_03021 | HMPREF0216_00312 | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: thx:Thet_0993 4.1e-20 ATP/cobalamin adenosyltransferase. | 0.677 |
| EKY23236.1 | cbiA | HMPREF0216_03021 | HMPREF0216_03179 | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.815 |
| EKY23236.1 | cobD | HMPREF0216_03021 | HMPREF0216_02319 | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.785 |
| EKY23236.1 | cobQ | HMPREF0216_03021 | HMPREF0216_02325 | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.778 |
| EKY23236.1 | cobS | HMPREF0216_03021 | HMPREF0216_02316 | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.757 |
| EKY23236.1 | cobT | HMPREF0216_03021 | HMPREF0216_02314 | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.781 |
| EKY25829.1 | EKY23236.1 | HMPREF0216_02315 | HMPREF0216_03021 | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | 0.565 |
| EKY25829.1 | EKY25831.1 | HMPREF0216_02315 | HMPREF0216_02317 | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: ere:EUBREC_1922 4.8e-10 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.969 |
| EKY25829.1 | EKY25834.1 | HMPREF0216_02315 | HMPREF0216_02320 | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | KEGG: cpe:CPE1040 7.5e-108 threonine-phosphate decarboxylase K04720. | 0.869 |
| EKY25829.1 | EKY26827.1 | HMPREF0216_02315 | HMPREF0216_01704 | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Putative cob(I)yrinic acid a,c-diamide adenosyltransferase; KEGG: cbk:CLL_A2924 4.0e-54 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; K00798 cob(I)alamin adenosyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.964 |
| EKY25829.1 | EKY29258.1 | HMPREF0216_02315 | HMPREF0216_00312 | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: thx:Thet_0993 4.1e-20 ATP/cobalamin adenosyltransferase. | 0.838 |
| EKY25829.1 | cbiA | HMPREF0216_02315 | HMPREF0216_03179 | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.953 |
| EKY25829.1 | cobD | HMPREF0216_02315 | HMPREF0216_02319 | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.979 |
| EKY25829.1 | cobQ | HMPREF0216_02315 | HMPREF0216_02325 | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.938 |
| EKY25829.1 | cobS | HMPREF0216_02315 | HMPREF0216_02316 | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.993 |
| EKY25829.1 | cobT | HMPREF0216_02315 | HMPREF0216_02314 | KEGG: cpr:CPR_1109 3.4e-48 hypothetical protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.982 |