| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY26604.1 | ffh | HMPREF0216_01789 | HMPREF0216_01788 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.986 |
| EKY26604.1 | ftsY | HMPREF0216_01789 | HMPREF0216_01790 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.673 |
| EKY26604.1 | rplS | HMPREF0216_01789 | HMPREF0216_01783 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.459 |
| EKY26604.1 | rpsP | HMPREF0216_01789 | HMPREF0216_01787 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Ribosomal protein S16; KEGG: apb:SAR116_1817 3.0e-17 ribosomal protein S16 K02959; Psort location: Cytoplasmic, score: 9.97; Belongs to the bacterial ribosomal protein bS16 family. | 0.821 |
| EKY27300.1 | ffh | HMPREF0216_01464 | HMPREF0216_01788 | Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 5.9e-10 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.905 |
| EKY27300.1 | ftsY | HMPREF0216_01464 | HMPREF0216_01790 | Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 5.9e-10 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.877 |
| EKY27300.1 | rplD | HMPREF0216_01464 | HMPREF0216_01152 | Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 5.9e-10 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.868 |
| EKY27300.1 | rplM | HMPREF0216_01464 | HMPREF0216_01189 | Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 5.9e-10 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.836 |
| EKY27300.1 | rplO | HMPREF0216_01464 | HMPREF0216_01170 | Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 5.9e-10 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.805 |
| EKY27300.1 | rplS | HMPREF0216_01464 | HMPREF0216_01783 | Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 5.9e-10 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.888 |
| EKY27300.1 | rpmF | HMPREF0216_01464 | HMPREF0216_01797 | Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 5.9e-10 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00. | Ribosomal protein L32; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL32 family. | 0.825 |
| EKY27300.1 | rpsP | HMPREF0216_01464 | HMPREF0216_01787 | Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 5.9e-10 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00. | Ribosomal protein S16; KEGG: apb:SAR116_1817 3.0e-17 ribosomal protein S16 K02959; Psort location: Cytoplasmic, score: 9.97; Belongs to the bacterial ribosomal protein bS16 family. | 0.878 |
| EKY27300.1 | secE | HMPREF0216_01464 | HMPREF0216_01475 | Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 5.9e-10 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.946 |
| ffh | EKY26604.1 | HMPREF0216_01788 | HMPREF0216_01789 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.986 |
| ffh | EKY27300.1 | HMPREF0216_01788 | HMPREF0216_01464 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Membrane protein insertase, YidC/Oxa1 family; KEGG: apb:SAR116_1502 5.9e-10 60 kDa inner membrane insertion protein K03217; Psort location: CytoplasmicMembrane, score: 10.00. | 0.905 |
| ffh | ftsY | HMPREF0216_01788 | HMPREF0216_01790 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.994 |
| ffh | rplD | HMPREF0216_01788 | HMPREF0216_01152 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.892 |
| ffh | rplM | HMPREF0216_01788 | HMPREF0216_01189 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.887 |
| ffh | rplO | HMPREF0216_01788 | HMPREF0216_01170 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.894 |
| ffh | rplS | HMPREF0216_01788 | HMPREF0216_01783 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.941 |
