| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY25395.1 | EKY26137.1 | HMPREF0216_02494 | HMPREF0216_02176 | Hydrolase, NUDIX family; KEGG: wch:wcw_0927 1.7e-07 putative (di)nucleoside polyphosphate hydrolase; Psort location: Cytoplasmic, score: 7.50. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.834 |
| EKY25395.1 | EKY26309.1 | HMPREF0216_02494 | HMPREF0216_02093 | Hydrolase, NUDIX family; KEGG: wch:wcw_0927 1.7e-07 putative (di)nucleoside polyphosphate hydrolase; Psort location: Cytoplasmic, score: 7.50. | Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 3.4e-18 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 7.50. | 0.790 |
| EKY25395.1 | EKY27840.1 | HMPREF0216_02494 | HMPREF0216_01197 | Hydrolase, NUDIX family; KEGG: wch:wcw_0927 1.7e-07 putative (di)nucleoside polyphosphate hydrolase; Psort location: Cytoplasmic, score: 7.50. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.781 |
| EKY25395.1 | folE | HMPREF0216_02494 | HMPREF0216_02173 | Hydrolase, NUDIX family; KEGG: wch:wcw_0927 1.7e-07 putative (di)nucleoside polyphosphate hydrolase; Psort location: Cytoplasmic, score: 7.50. | GTP cyclohydrolase I; KEGG: cpf:CPF_1274 9.5e-69 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50. | 0.406 |
| EKY25395.1 | ribBA | HMPREF0216_02494 | HMPREF0216_00786 | Hydrolase, NUDIX family; KEGG: wch:wcw_0927 1.7e-07 putative (di)nucleoside polyphosphate hydrolase; Psort location: Cytoplasmic, score: 7.50. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.787 |
| EKY26137.1 | EKY25395.1 | HMPREF0216_02176 | HMPREF0216_02494 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Hydrolase, NUDIX family; KEGG: wch:wcw_0927 1.7e-07 putative (di)nucleoside polyphosphate hydrolase; Psort location: Cytoplasmic, score: 7.50. | 0.834 |
| EKY26137.1 | EKY26218.1 | HMPREF0216_02176 | HMPREF0216_02257 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.603 |
| EKY26137.1 | EKY26309.1 | HMPREF0216_02176 | HMPREF0216_02093 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 3.4e-18 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 7.50. | 0.907 |
| EKY26137.1 | EKY27241.1 | HMPREF0216_02176 | HMPREF0216_01493 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | MazG family protein; KEGG: bmd:BMD_0076 1.2e-102 tetrapyrrole methylase family protein / MazG family protein K02499; Psort location: Cytoplasmic, score: 7.50. | 0.469 |
| EKY26137.1 | EKY27840.1 | HMPREF0216_02176 | HMPREF0216_01197 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.831 |
| EKY26137.1 | EKY28371.1 | HMPREF0216_02176 | HMPREF0216_00893 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Hydrolase, NUDIX family; KEGG: ooe:OEOE_1181 3.8e-33 ADP-ribose pyrophosphatase; K03574 7,8-dihydro-8-oxoguanine triphosphatase; Belongs to the Nudix hydrolase family. | 0.834 |
| EKY26137.1 | EKY29695.1 | HMPREF0216_02176 | HMPREF0216_00103 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Mutator mutT protein; KEGG: cbk:CLL_A2065 8.8e-50 mutT; MutT/NUDIX family protein; K03574 7,8-dihydro-8-oxoguanine triphosphatase; Psort location: Cytoplasmic, score: 7.50. | 0.834 |
| EKY26137.1 | folE | HMPREF0216_02176 | HMPREF0216_02173 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; KEGG: cpf:CPF_1274 9.5e-69 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50. | 0.999 |
| EKY26137.1 | ribBA | HMPREF0216_02176 | HMPREF0216_00786 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.976 |
| EKY26218.1 | EKY26137.1 | HMPREF0216_02257 | HMPREF0216_02176 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.603 |
| EKY26218.1 | EKY26309.1 | HMPREF0216_02257 | HMPREF0216_02093 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 3.4e-18 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 7.50. | 0.800 |
| EKY26218.1 | EKY27241.1 | HMPREF0216_02257 | HMPREF0216_01493 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | MazG family protein; KEGG: bmd:BMD_0076 1.2e-102 tetrapyrrole methylase family protein / MazG family protein K02499; Psort location: Cytoplasmic, score: 7.50. | 0.835 |
| EKY26218.1 | EKY27840.1 | HMPREF0216_02257 | HMPREF0216_01197 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.799 |
| EKY26218.1 | EKY28371.1 | HMPREF0216_02257 | HMPREF0216_00893 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Hydrolase, NUDIX family; KEGG: ooe:OEOE_1181 3.8e-33 ADP-ribose pyrophosphatase; K03574 7,8-dihydro-8-oxoguanine triphosphatase; Belongs to the Nudix hydrolase family. | 0.496 |
| EKY26218.1 | EKY29695.1 | HMPREF0216_02257 | HMPREF0216_00103 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Mutator mutT protein; KEGG: cbk:CLL_A2065 8.8e-50 mutT; MutT/NUDIX family protein; K03574 7,8-dihydro-8-oxoguanine triphosphatase; Psort location: Cytoplasmic, score: 7.50. | 0.555 |