| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY25398.1 | EKY26087.1 | HMPREF0216_02498 | HMPREF0216_02126 | Hypothetical protein; KEGG: clo:HMPREF0868_0202 3.2e-22 isochorismatase family protein; Psort location: Cytoplasmic, score: 7.50. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.767 |
| EKY25398.1 | EKY27130.1 | HMPREF0216_02498 | HMPREF0216_01541 | Hypothetical protein; KEGG: clo:HMPREF0868_0202 3.2e-22 isochorismatase family protein; Psort location: Cytoplasmic, score: 7.50. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 8.1e-24 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family. | 0.650 |
| EKY25398.1 | EKY27256.1 | HMPREF0216_02498 | HMPREF0216_01508 | Hypothetical protein; KEGG: clo:HMPREF0868_0202 3.2e-22 isochorismatase family protein; Psort location: Cytoplasmic, score: 7.50. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.803 |
| EKY25398.1 | EKY28346.1 | HMPREF0216_02498 | HMPREF0216_00868 | Hypothetical protein; KEGG: clo:HMPREF0868_0202 3.2e-22 isochorismatase family protein; Psort location: Cytoplasmic, score: 7.50. | Selenium-dependent molybdenum hydroxylase 1; KEGG: cbo:CBO2881 3.2e-299 xdhAC; xanthine dehydrogenase family protein, molybdopterin-binding subunit; Psort location: CytoplasmicMembrane, score: 8.78. | 0.800 |
| EKY25398.1 | EKY29580.1 | HMPREF0216_02498 | HMPREF0216_00163 | Hypothetical protein; KEGG: clo:HMPREF0868_0202 3.2e-22 isochorismatase family protein; Psort location: Cytoplasmic, score: 7.50. | KEGG: cdc:CD196_2211 1.8e-83 nadC; nicotinate-nucleotide pyrophosphorylase; K00767 nicotinate-nucleotide pyrophosphorylase (carboxylating); Psort location: Cytoplasmic, score: 9.67; Belongs to the NadC/ModD family. | 0.624 |
| EKY25398.1 | deoD | HMPREF0216_02498 | HMPREF0216_02663 | Hypothetical protein; KEGG: clo:HMPREF0868_0202 3.2e-22 isochorismatase family protein; Psort location: Cytoplasmic, score: 7.50. | KEGG: cno:NT01CX_2329 4.4e-80 deoD; purine nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 9.67. | 0.795 |
| EKY25398.1 | nadD | HMPREF0216_02498 | HMPREF0216_03301 | Hypothetical protein; KEGG: clo:HMPREF0868_0202 3.2e-22 isochorismatase family protein; Psort location: Cytoplasmic, score: 7.50. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.580 |
| EKY25398.1 | nadE | HMPREF0216_02498 | HMPREF0216_02039 | Hypothetical protein; KEGG: clo:HMPREF0868_0202 3.2e-22 isochorismatase family protein; Psort location: Cytoplasmic, score: 7.50. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.674 |
| EKY25416.1 | EKY26087.1 | HMPREF0216_02516 | HMPREF0216_02126 | Hydrolase, NUDIX family; KEGG: clj:CLJU_c19510 2.0e-59 putative pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.663 |
| EKY25416.1 | EKY26192.1 | HMPREF0216_02516 | HMPREF0216_02231 | Hydrolase, NUDIX family; KEGG: clj:CLJU_c19510 2.0e-59 putative pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50. | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | 0.806 |
| EKY25416.1 | EKY27130.1 | HMPREF0216_02516 | HMPREF0216_01541 | Hydrolase, NUDIX family; KEGG: clj:CLJU_c19510 2.0e-59 putative pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 8.1e-24 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family. | 0.850 |
| EKY25416.1 | EKY28346.1 | HMPREF0216_02516 | HMPREF0216_00868 | Hydrolase, NUDIX family; KEGG: clj:CLJU_c19510 2.0e-59 putative pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50. | Selenium-dependent molybdenum hydroxylase 1; KEGG: cbo:CBO2881 3.2e-299 xdhAC; xanthine dehydrogenase family protein, molybdopterin-binding subunit; Psort location: CytoplasmicMembrane, score: 8.78. | 0.785 |
| EKY25416.1 | EKY29580.1 | HMPREF0216_02516 | HMPREF0216_00163 | Hydrolase, NUDIX family; KEGG: clj:CLJU_c19510 2.0e-59 putative pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50. | KEGG: cdc:CD196_2211 1.8e-83 nadC; nicotinate-nucleotide pyrophosphorylase; K00767 nicotinate-nucleotide pyrophosphorylase (carboxylating); Psort location: Cytoplasmic, score: 9.67; Belongs to the NadC/ModD family. | 0.793 |
| EKY25416.1 | nadD | HMPREF0216_02516 | HMPREF0216_03301 | Hydrolase, NUDIX family; KEGG: clj:CLJU_c19510 2.0e-59 putative pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.807 |
| EKY25416.1 | nadE | HMPREF0216_02516 | HMPREF0216_02039 | Hydrolase, NUDIX family; KEGG: clj:CLJU_c19510 2.0e-59 putative pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.904 |
| EKY26087.1 | EKY25398.1 | HMPREF0216_02126 | HMPREF0216_02498 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein; KEGG: clo:HMPREF0868_0202 3.2e-22 isochorismatase family protein; Psort location: Cytoplasmic, score: 7.50. | 0.767 |
| EKY26087.1 | EKY25416.1 | HMPREF0216_02126 | HMPREF0216_02516 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hydrolase, NUDIX family; KEGG: clj:CLJU_c19510 2.0e-59 putative pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50. | 0.663 |
| EKY26087.1 | EKY26192.1 | HMPREF0216_02126 | HMPREF0216_02231 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. | 0.771 |
| EKY26087.1 | EKY27130.1 | HMPREF0216_02126 | HMPREF0216_01541 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 8.1e-24 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family. | 0.898 |
| EKY26087.1 | EKY27256.1 | HMPREF0216_02126 | HMPREF0216_01508 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.661 |