| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22493.1 | EKY26107.1 | HMPREF0216_03216 | HMPREF0216_02146 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | 0.629 |
| EKY22493.1 | EKY26109.1 | HMPREF0216_03216 | HMPREF0216_02148 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: ctc:CTC01807 1.6e-52 putative 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 7.50. | 0.432 |
| EKY22493.1 | EKY26110.1 | HMPREF0216_03216 | HMPREF0216_02149 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.912 |
| EKY22493.1 | EKY28519.1 | HMPREF0216_03216 | HMPREF0216_00717 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | KEGG: cno:NT01CX_1210 7.0e-160 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.67. | 0.870 |
| EKY22493.1 | EKY28521.1 | HMPREF0216_03216 | HMPREF0216_00719 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | KEGG: aco:Amico_0519 1.2e-77 homoserine dehydrogenase K00003. | 0.769 |
| EKY22493.1 | luxS | HMPREF0216_03216 | HMPREF0216_02147 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.816 |
| EKY24038.1 | EKY26107.1 | HMPREF0216_02797 | HMPREF0216_02146 | DNA-binding helix-turn-helix protein. | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | 0.468 |
| EKY24038.1 | EKY26109.1 | HMPREF0216_02797 | HMPREF0216_02148 | DNA-binding helix-turn-helix protein. | Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: ctc:CTC01807 1.6e-52 putative 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 7.50. | 0.516 |
| EKY24038.1 | EKY26110.1 | HMPREF0216_02797 | HMPREF0216_02149 | DNA-binding helix-turn-helix protein. | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.941 |
| EKY24038.1 | fhs | HMPREF0216_02797 | HMPREF0216_02543 | DNA-binding helix-turn-helix protein. | KEGG: cbe:Cbei_0101 2.5e-251 formate--tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 7.50. | 0.426 |
| EKY24038.1 | metK | HMPREF0216_02797 | HMPREF0216_03355 | DNA-binding helix-turn-helix protein. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.818 |
| EKY26107.1 | EKY22493.1 | HMPREF0216_02146 | HMPREF0216_03216 | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | 0.629 |
| EKY26107.1 | EKY24038.1 | HMPREF0216_02146 | HMPREF0216_02797 | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | DNA-binding helix-turn-helix protein. | 0.468 |
| EKY26107.1 | EKY26109.1 | HMPREF0216_02146 | HMPREF0216_02148 | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: ctc:CTC01807 1.6e-52 putative 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 7.50. | 0.928 |
| EKY26107.1 | EKY26110.1 | HMPREF0216_02146 | HMPREF0216_02149 | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.999 |
| EKY26107.1 | EKY28518.1 | HMPREF0216_02146 | HMPREF0216_00716 | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | KEGG: cdf:CD1580 1.1e-106 hom2; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | 0.691 |
| EKY26107.1 | EKY28519.1 | HMPREF0216_02146 | HMPREF0216_00717 | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | KEGG: cno:NT01CX_1210 7.0e-160 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.67. | 0.520 |
| EKY26107.1 | EKY28521.1 | HMPREF0216_02146 | HMPREF0216_00719 | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | KEGG: aco:Amico_0519 1.2e-77 homoserine dehydrogenase K00003. | 0.677 |
| EKY26107.1 | fhs | HMPREF0216_02146 | HMPREF0216_02543 | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbe:Cbei_0101 2.5e-251 formate--tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 7.50. | 0.905 |
| EKY26107.1 | luxS | HMPREF0216_02146 | HMPREF0216_02147 | KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.880 |