| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22493.1 | EKY26117.1 | HMPREF0216_03216 | HMPREF0216_02156 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | 0.462 |
| EKY22493.1 | EKY28191.1 | HMPREF0216_03216 | HMPREF0216_01035 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | 0.822 |
| EKY22493.1 | EKY28192.1 | HMPREF0216_03216 | HMPREF0216_01036 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein. | 0.769 |
| EKY22493.1 | EKY28193.1 | HMPREF0216_03216 | HMPREF0216_01037 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | Putative L-serine dehydratase, iron-sulfur-dependent, beta subunit. | 0.769 |
| EKY22493.1 | EKY28521.1 | HMPREF0216_03216 | HMPREF0216_00719 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | KEGG: aco:Amico_0519 1.2e-77 homoserine dehydrogenase K00003. | 0.769 |
| EKY22493.1 | glyA | HMPREF0216_03216 | HMPREF0216_02267 | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.469 |
| EKY26116.1 | EKY26117.1 | HMPREF0216_02155 | HMPREF0216_02156 | Hypothetical protein. | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | 0.507 |
| EKY26116.1 | EKY26118.1 | HMPREF0216_02155 | HMPREF0216_02157 | Hypothetical protein. | Hypothetical protein; KEGG: bpf:BpOF4_10935 0.0042 dihydroxyacid dehydratase phosphogluconate dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 7.50. | 0.467 |
| EKY26117.1 | EKY22493.1 | HMPREF0216_02156 | HMPREF0216_03216 | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | KEGG: cbt:CLH_0975 5.9e-163 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | 0.462 |
| EKY26117.1 | EKY26116.1 | HMPREF0216_02156 | HMPREF0216_02155 | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | Hypothetical protein. | 0.507 |
| EKY26117.1 | EKY26118.1 | HMPREF0216_02156 | HMPREF0216_02157 | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | Hypothetical protein; KEGG: bpf:BpOF4_10935 0.0042 dihydroxyacid dehydratase phosphogluconate dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 7.50. | 0.947 |
| EKY26117.1 | EKY28191.1 | HMPREF0216_02156 | HMPREF0216_01035 | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | 0.430 |
| EKY26117.1 | EKY28192.1 | HMPREF0216_02156 | HMPREF0216_01036 | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | Hypothetical protein. | 0.430 |
| EKY26117.1 | EKY28193.1 | HMPREF0216_02156 | HMPREF0216_01037 | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | Putative L-serine dehydratase, iron-sulfur-dependent, beta subunit. | 0.430 |
| EKY26117.1 | EKY28518.1 | HMPREF0216_02156 | HMPREF0216_00716 | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | KEGG: cdf:CD1580 1.1e-106 hom2; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | 0.486 |
| EKY26117.1 | EKY28521.1 | HMPREF0216_02156 | HMPREF0216_00719 | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | KEGG: aco:Amico_0519 1.2e-77 homoserine dehydrogenase K00003. | 0.483 |
| EKY26117.1 | EKY29029.1 | HMPREF0216_02156 | HMPREF0216_00388 | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | Bacterial sugar transferase; KEGG: nmc:NMC0399 6.9e-66 PglB2 K01955; Psort location: CytoplasmicMembrane, score: 9.99. | 0.416 |
| EKY26117.1 | glyA | HMPREF0216_02156 | HMPREF0216_02267 | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.491 |
| EKY26118.1 | EKY26116.1 | HMPREF0216_02157 | HMPREF0216_02155 | Hypothetical protein; KEGG: bpf:BpOF4_10935 0.0042 dihydroxyacid dehydratase phosphogluconate dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein. | 0.467 |
| EKY26118.1 | EKY26117.1 | HMPREF0216_02157 | HMPREF0216_02156 | Hypothetical protein; KEGG: bpf:BpOF4_10935 0.0042 dihydroxyacid dehydratase phosphogluconate dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 7.50. | ACT domain protein; KEGG: fpl:Ferp_0598 2.8e-09 phosphoserine phosphatase SerB K01079; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0237 family. | 0.947 |