| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY23227.1 | EKY26131.1 | HMPREF0216_03012 | HMPREF0216_02170 | Branched-chain-amino-acid transaminase; KEGG: ckl:CKL_3620 3.3e-146 ilvE3; branched-chain amino acid aminotransferase K00826; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbe:Cbei_4120 1.3e-71 glutamine amidotransferase of anthranilate synthase; K01664 para-aminobenzoate synthetase component II; Psort location: Cytoplasmic, score: 7.50. | 0.687 |
| EKY23227.1 | EKY26132.1 | HMPREF0216_03012 | HMPREF0216_02171 | Branched-chain-amino-acid transaminase; KEGG: ckl:CKL_3620 3.3e-146 ilvE3; branched-chain amino acid aminotransferase K00826; Psort location: Cytoplasmic, score: 7.50. | Putative aminodeoxychorismate synthase, component I; KEGG: cbe:Cbei_4119 5.3e-146 para-aminobenzoate synthase, subunit I K01665; Psort location: Cytoplasmic, score: 9.67. | 0.695 |
| EKY23227.1 | EKY26133.1 | HMPREF0216_03012 | HMPREF0216_02172 | Branched-chain-amino-acid transaminase; KEGG: ckl:CKL_3620 3.3e-146 ilvE3; branched-chain amino acid aminotransferase K00826; Psort location: Cytoplasmic, score: 7.50. | Aminotransferase, class IV; KEGG: cpe:CPE1018 7.1e-64 4-amino-4-deoxychorismate lyase; K02619 4-amino-4-deoxychorismate lyase. | 0.783 |
| EKY23227.1 | EKY26136.1 | HMPREF0216_03012 | HMPREF0216_02175 | Branched-chain-amino-acid transaminase; KEGG: ckl:CKL_3620 3.3e-146 ilvE3; branched-chain amino acid aminotransferase K00826; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbe:Cbei_0206 5.9e-92 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 7.50. | 0.724 |
| EKY23227.1 | EKY26137.1 | HMPREF0216_03012 | HMPREF0216_02176 | Branched-chain-amino-acid transaminase; KEGG: ckl:CKL_3620 3.3e-146 ilvE3; branched-chain amino acid aminotransferase K00826; Psort location: Cytoplasmic, score: 7.50. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.893 |
| EKY24632.1 | EKY26136.1 | HMPREF0216_02662 | HMPREF0216_02175 | Protein FolC; KEGG: cbk:CLL_A2503 7.7e-138 folylpolyglutamate synthase K11754; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbe:Cbei_0206 5.9e-92 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 7.50. | 0.996 |
| EKY24632.1 | EKY26137.1 | HMPREF0216_02662 | HMPREF0216_02176 | Protein FolC; KEGG: cbk:CLL_A2503 7.7e-138 folylpolyglutamate synthase K11754; Psort location: Cytoplasmic, score: 7.50. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.991 |
| EKY24632.1 | folE | HMPREF0216_02662 | HMPREF0216_02173 | Protein FolC; KEGG: cbk:CLL_A2503 7.7e-138 folylpolyglutamate synthase K11754; Psort location: Cytoplasmic, score: 7.50. | GTP cyclohydrolase I; KEGG: cpf:CPF_1274 9.5e-69 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50. | 0.670 |
| EKY24632.1 | thyA | HMPREF0216_02662 | HMPREF0216_00285 | Protein FolC; KEGG: cbk:CLL_A2503 7.7e-138 folylpolyglutamate synthase K11754; Psort location: Cytoplasmic, score: 7.50. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.842 |
| EKY26110.1 | EKY26136.1 | HMPREF0216_02149 | HMPREF0216_02175 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbe:Cbei_0206 5.9e-92 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 7.50. | 0.661 |
| EKY26110.1 | folE | HMPREF0216_02149 | HMPREF0216_02173 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | GTP cyclohydrolase I; KEGG: cpf:CPF_1274 9.5e-69 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50. | 0.459 |
| EKY26110.1 | thyA | HMPREF0216_02149 | HMPREF0216_00285 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.828 |
| EKY26131.1 | EKY23227.1 | HMPREF0216_02170 | HMPREF0216_03012 | KEGG: cbe:Cbei_4120 1.3e-71 glutamine amidotransferase of anthranilate synthase; K01664 para-aminobenzoate synthetase component II; Psort location: Cytoplasmic, score: 7.50. | Branched-chain-amino-acid transaminase; KEGG: ckl:CKL_3620 3.3e-146 ilvE3; branched-chain amino acid aminotransferase K00826; Psort location: Cytoplasmic, score: 7.50. | 0.687 |
| EKY26131.1 | EKY26132.1 | HMPREF0216_02170 | HMPREF0216_02171 | KEGG: cbe:Cbei_4120 1.3e-71 glutamine amidotransferase of anthranilate synthase; K01664 para-aminobenzoate synthetase component II; Psort location: Cytoplasmic, score: 7.50. | Putative aminodeoxychorismate synthase, component I; KEGG: cbe:Cbei_4119 5.3e-146 para-aminobenzoate synthase, subunit I K01665; Psort location: Cytoplasmic, score: 9.67. | 0.999 |
| EKY26131.1 | EKY26133.1 | HMPREF0216_02170 | HMPREF0216_02172 | KEGG: cbe:Cbei_4120 1.3e-71 glutamine amidotransferase of anthranilate synthase; K01664 para-aminobenzoate synthetase component II; Psort location: Cytoplasmic, score: 7.50. | Aminotransferase, class IV; KEGG: cpe:CPE1018 7.1e-64 4-amino-4-deoxychorismate lyase; K02619 4-amino-4-deoxychorismate lyase. | 0.968 |
| EKY26131.1 | EKY26135.1 | HMPREF0216_02170 | HMPREF0216_02174 | KEGG: cbe:Cbei_4120 1.3e-71 glutamine amidotransferase of anthranilate synthase; K01664 para-aminobenzoate synthetase component II; Psort location: Cytoplasmic, score: 7.50. | HDIG domain protein; KEGG: dap:Dacet_1921 1.0e-05 metal dependent phosphohydrolase K06950. | 0.590 |
| EKY26131.1 | EKY26136.1 | HMPREF0216_02170 | HMPREF0216_02175 | KEGG: cbe:Cbei_4120 1.3e-71 glutamine amidotransferase of anthranilate synthase; K01664 para-aminobenzoate synthetase component II; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbe:Cbei_0206 5.9e-92 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 7.50. | 0.863 |
| EKY26131.1 | EKY26137.1 | HMPREF0216_02170 | HMPREF0216_02176 | KEGG: cbe:Cbei_4120 1.3e-71 glutamine amidotransferase of anthranilate synthase; K01664 para-aminobenzoate synthetase component II; Psort location: Cytoplasmic, score: 7.50. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.906 |
| EKY26131.1 | folE | HMPREF0216_02170 | HMPREF0216_02173 | KEGG: cbe:Cbei_4120 1.3e-71 glutamine amidotransferase of anthranilate synthase; K01664 para-aminobenzoate synthetase component II; Psort location: Cytoplasmic, score: 7.50. | GTP cyclohydrolase I; KEGG: cpf:CPF_1274 9.5e-69 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50. | 0.717 |
| EKY26132.1 | EKY23227.1 | HMPREF0216_02171 | HMPREF0216_03012 | Putative aminodeoxychorismate synthase, component I; KEGG: cbe:Cbei_4119 5.3e-146 para-aminobenzoate synthase, subunit I K01665; Psort location: Cytoplasmic, score: 9.67. | Branched-chain-amino-acid transaminase; KEGG: ckl:CKL_3620 3.3e-146 ilvE3; branched-chain amino acid aminotransferase K00826; Psort location: Cytoplasmic, score: 7.50. | 0.695 |