Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKY26192.1LPXTG-motif protein cell wall anchor domain protein; Belongs to the 5'-nucleotidase family. (632 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
    
 0.851
EKY25748.1
Ser/Thr phosphatase family protein.
  
 
 0.850
udk
Uridine kinase.
 
 
  0.847
EKY25481.1
5'-nucleotidase protein; KEGG: taf:THA_1701 5.7e-94 2',3'-cyclic-nucleotide 2'-phosphodiesterase; K01119 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family.
 
  
0.845
EKY27130.1
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 8.1e-24 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family.
  
 
  0.843
EKY24034.1
S1 RNA binding domain protein.
    
  0.842
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.829
EKY26172.1
5'-nucleotidase protein.
 
  
0.828
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.825
EKY28194.1
Phosphoribulokinase/uridine kinase family protein.
  
 
  0.821
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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