node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EKY22374.1 | EKY26229.1 | HMPREF0216_03262 | HMPREF0216_02268 | Pseudouridylate synthase; KEGG: cbe:Cbei_0345 9.1e-96 pseudouridine synthase; K06183 ribosomal small subunit pseudouridine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the pseudouridine synthase RsuA family. | Exodeoxyribonuclease III. | 0.876 |
EKY26229.1 | EKY22374.1 | HMPREF0216_02268 | HMPREF0216_03262 | Exodeoxyribonuclease III. | Pseudouridylate synthase; KEGG: cbe:Cbei_0345 9.1e-96 pseudouridine synthase; K06183 ribosomal small subunit pseudouridine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the pseudouridine synthase RsuA family. | 0.876 |
EKY26229.1 | EKY27039.1 | HMPREF0216_02268 | HMPREF0216_01642 | Exodeoxyribonuclease III. | KEGG: cbk:CLL_A0132 4.2e-66 3-methyladenine DNA glycosylase K03652; Psort location: Cytoplasmic, score: 7.50; Belongs to the DNA glycosylase MPG family. | 0.873 |
EKY26229.1 | EKY27305.1 | HMPREF0216_02268 | HMPREF0216_01469 | Exodeoxyribonuclease III. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.955 |
EKY26229.1 | EKY28580.1 | HMPREF0216_02268 | HMPREF0216_00633 | Exodeoxyribonuclease III. | KEGG: cbt:CLH_0367 2.4e-111 8-oxoguanine DNA glycosylase; K03660 N-glycosylase/DNA lyase; Psort location: Cytoplasmic, score: 7.50. | 0.927 |
EKY26229.1 | hfq | HMPREF0216_02268 | HMPREF0216_02890 | Exodeoxyribonuclease III. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.827 |
EKY26229.1 | nfo | HMPREF0216_02268 | HMPREF0216_00551 | Exodeoxyribonuclease III. | Apurinic endonuclease; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.904 |
EKY26229.1 | nth | HMPREF0216_02268 | HMPREF0216_01011 | Exodeoxyribonuclease III. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.998 |
EKY26229.1 | polA | HMPREF0216_02268 | HMPREF0216_02185 | Exodeoxyribonuclease III. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
EKY26229.1 | tadA | HMPREF0216_02268 | HMPREF0216_02607 | Exodeoxyribonuclease III. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.853 |
EKY26229.1 | ung | HMPREF0216_02268 | HMPREF0216_02896 | Exodeoxyribonuclease III. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.893 |
EKY27039.1 | EKY26229.1 | HMPREF0216_01642 | HMPREF0216_02268 | KEGG: cbk:CLL_A0132 4.2e-66 3-methyladenine DNA glycosylase K03652; Psort location: Cytoplasmic, score: 7.50; Belongs to the DNA glycosylase MPG family. | Exodeoxyribonuclease III. | 0.873 |
EKY27305.1 | EKY26229.1 | HMPREF0216_01469 | HMPREF0216_02268 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III. | 0.955 |
EKY27305.1 | polA | HMPREF0216_01469 | HMPREF0216_02185 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
EKY27305.1 | ung | HMPREF0216_01469 | HMPREF0216_02896 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.776 |
EKY28580.1 | EKY26229.1 | HMPREF0216_00633 | HMPREF0216_02268 | KEGG: cbt:CLH_0367 2.4e-111 8-oxoguanine DNA glycosylase; K03660 N-glycosylase/DNA lyase; Psort location: Cytoplasmic, score: 7.50. | Exodeoxyribonuclease III. | 0.927 |
EKY28580.1 | nfo | HMPREF0216_00633 | HMPREF0216_00551 | KEGG: cbt:CLH_0367 2.4e-111 8-oxoguanine DNA glycosylase; K03660 N-glycosylase/DNA lyase; Psort location: Cytoplasmic, score: 7.50. | Apurinic endonuclease; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.561 |
EKY28580.1 | nth | HMPREF0216_00633 | HMPREF0216_01011 | KEGG: cbt:CLH_0367 2.4e-111 8-oxoguanine DNA glycosylase; K03660 N-glycosylase/DNA lyase; Psort location: Cytoplasmic, score: 7.50. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.512 |
EKY28580.1 | polA | HMPREF0216_00633 | HMPREF0216_02185 | KEGG: cbt:CLH_0367 2.4e-111 8-oxoguanine DNA glycosylase; K03660 N-glycosylase/DNA lyase; Psort location: Cytoplasmic, score: 7.50. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.601 |
hfq | EKY26229.1 | HMPREF0216_02890 | HMPREF0216_02268 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Exodeoxyribonuclease III. | 0.827 |