STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proSproline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (574 aa)    
Predicted Functional Partners:
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
   
 0.990
gltX
glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 0.944
leuS
leucine--tRNA ligase; KEGG: cpf:CPF_0657 0. leuS; leucyl-tRNA synthetase K01869; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 0.936
glnS
glutamine--tRNA ligase; KEGG: ccb:Clocel_3324 1.3e-275 glutaminyl-tRNA synthetase; K01886 glutaminyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97.
  
 0.922
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 0.899
EKY26279.1
arginine--tRNA ligase domain protein; KEGG: cbt:CLH_2328 2.0e-45 argS; arginyl-tRNA synthetase K01887; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.874
lysS
lysine--tRNA ligase; KEGG: cbk:CLL_A0178 6.1e-232 lysS; lysyl-tRNA synthetase K04567; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.874
EKY23406.1
DALR anticodon binding domain protein; KEGG: aoe:Clos_2740 7.9e-97 argS; arginyl-tRNA synthetase K01887; Psort location: Cytoplasmic, score: 9.67; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.874
EKY23407.1
arginine--tRNA ligase domain protein; KEGG: aoe:Clos_2740 1.7e-78 argS; arginyl-tRNA synthetase K01887; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.874
EKY23703.1
asparagine--tRNA ligase; KEGG: cbe:Cbei_0076 4.4e-135 asnC; asparaginyl-tRNA synthetase K01893; Psort location: Cytoplasmic, score: 10.00.
  
 0.862
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.