STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EKY25391.1Hypothetical protein; KEGG: spu:578198 1.9e-09 similar to triple functional domain (PTPRF interacting); K08810 triple functional domain protein; Psort location: Cytoplasmic, score: 7.50. (231 aa)    
Predicted Functional Partners:
EKY27374.1
Diguanylate cyclase domain protein.
  
  
 0.747
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.651
EKY26293.1
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; KEGG: cno:NT01CX_2157 1.4e-26 N-acetylmuramoyl-L-alanine amidase CwlL precursor (cellwall hydrolase) (autolysin) K01447.
  
  
 0.624
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 
 0.616
EKY29047.1
Type VII secretion protein EssC; KEGG: eci:UTI89_C0905 3.2e-12 ftsK; DNA translocase FtsK K03466; Psort location: CytoplasmicMembrane, score: 8.78.
  
 
 0.581
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.534
EKY23482.1
Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.531
EKY25392.1
Threonine/alanine tRNA ligase second additional domain protein; KEGG: btl:BALH_3259 8.3e-54 alaS; alanine--tRNA ligase K07050; Psort location: Cytoplasmic, score: 9.97.
       0.497
EKY26428.1
Chorismate mutase; KEGG: cbe:Cbei_4573 1.1e-122 chorismate mutase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97.
       0.487
EKY29573.1
BclA domain protein; KEGG: isc:IscW_ISCW014473 3.0e-26 basement membrane collagen, putative; Psort location: Cytoplasmic, score: 7.50.
 
     0.479
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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