Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
EKY25402.1Heavy metal-associated domain protein; KEGG: cbt:CLH_3060 3.5e-16 copper-transporting P-type ATPase; Psort location: Cytoplasmic, score: 7.50. (69 aa)    
Predicted Functional Partners:
EKY25403.1
Copper-exporting ATPase; KEGG: cbe:Cbei_4802 0. heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.902
EKY25404.1
Putative copper-sensing transcriptional repressor CsoR; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.855
EKY26871.1
Hypothetical protein; KEGG: str:Sterm_3002 2.5e-06 hypothetical protein; K03775 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD.
  
 
 0.831
EKY28593.1
Cadmium-exporting ATPase; KEGG: amt:Amet_0130 3.0e-232 heavy metal translocating P-type ATPase; K01534 Cd2+/Zn2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99.
  
 
 0.761
EKY22763.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.645
EKY25418.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
     0.426
topB
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
  
   
 0.424
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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