| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY25312.1 | EKY25313.1 | HMPREF0216_02535 | HMPREF0216_02536 | KEGG: bmq:BMQ_0607 1.5e-40 metallo-beta-lactamase family protein; Psort location: Cytoplasmic, score: 7.50. | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | 0.402 |
| EKY25313.1 | EKY25312.1 | HMPREF0216_02536 | HMPREF0216_02535 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | KEGG: bmq:BMQ_0607 1.5e-40 metallo-beta-lactamase family protein; Psort location: Cytoplasmic, score: 7.50. | 0.402 |
| EKY25313.1 | EKY25314.1 | HMPREF0216_02536 | HMPREF0216_02537 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Phospholipase, patatin family; KEGG: fnu:FN0508 3.4e-12 serine protease. | 0.608 |
| EKY25313.1 | EKY29072.1 | HMPREF0216_02536 | HMPREF0216_00431 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Pyridoxal-dependent decarboxylase, pyridoxal binding domain protein; KEGG: bvu:BVU_4042 5.1e-86 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 7.50. | 0.689 |
| EKY25313.1 | EKY29413.1 | HMPREF0216_02536 | HMPREF0216_00274 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.87. | 0.556 |
| EKY25313.1 | dapF | HMPREF0216_02536 | HMPREF0216_01578 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.816 |
| EKY25313.1 | lysA | HMPREF0216_02536 | HMPREF0216_00461 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.924 |
| EKY25313.1 | murE | HMPREF0216_02536 | HMPREF0216_01561 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.795 |
| EKY25313.1 | murF | HMPREF0216_02536 | HMPREF0216_01562 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.462 |
| EKY25313.1 | rnpA | HMPREF0216_02536 | HMPREF0216_01466 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.645 |
| EKY25313.1 | rpsP | HMPREF0216_02536 | HMPREF0216_01787 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Ribosomal protein S16; KEGG: apb:SAR116_1817 3.0e-17 ribosomal protein S16 K02959; Psort location: Cytoplasmic, score: 9.97; Belongs to the bacterial ribosomal protein bS16 family. | 0.443 |
| EKY25314.1 | EKY25313.1 | HMPREF0216_02537 | HMPREF0216_02536 | Phospholipase, patatin family; KEGG: fnu:FN0508 3.4e-12 serine protease. | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | 0.608 |
| EKY29072.1 | EKY25313.1 | HMPREF0216_00431 | HMPREF0216_02536 | Pyridoxal-dependent decarboxylase, pyridoxal binding domain protein; KEGG: bvu:BVU_4042 5.1e-86 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 7.50. | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | 0.689 |
| EKY29072.1 | dapF | HMPREF0216_00431 | HMPREF0216_01578 | Pyridoxal-dependent decarboxylase, pyridoxal binding domain protein; KEGG: bvu:BVU_4042 5.1e-86 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 7.50. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.826 |
| EKY29072.1 | murE | HMPREF0216_00431 | HMPREF0216_01561 | Pyridoxal-dependent decarboxylase, pyridoxal binding domain protein; KEGG: bvu:BVU_4042 5.1e-86 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.645 |
| EKY29072.1 | murF | HMPREF0216_00431 | HMPREF0216_01562 | Pyridoxal-dependent decarboxylase, pyridoxal binding domain protein; KEGG: bvu:BVU_4042 5.1e-86 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.590 |
| EKY29413.1 | EKY25313.1 | HMPREF0216_00274 | HMPREF0216_02536 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.87. | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | 0.556 |
| dapF | EKY25313.1 | HMPREF0216_01578 | HMPREF0216_02536 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | 0.816 |
| dapF | EKY29072.1 | HMPREF0216_01578 | HMPREF0216_00431 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Pyridoxal-dependent decarboxylase, pyridoxal binding domain protein; KEGG: bvu:BVU_4042 5.1e-86 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 7.50. | 0.826 |
| dapF | lysA | HMPREF0216_01578 | HMPREF0216_00461 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.967 |