| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22752.1 | EKY25257.1 | HMPREF0216_03116 | HMPREF0216_02547 | Stage II sporulation protein P. | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | 0.902 |
| EKY22752.1 | EKY26645.1 | HMPREF0216_03116 | HMPREF0216_01830 | Stage II sporulation protein P. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.858 |
| EKY22752.1 | EKY26660.1 | HMPREF0216_03116 | HMPREF0216_01845 | Stage II sporulation protein P. | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.764 |
| EKY22752.1 | EKY26662.1 | HMPREF0216_03116 | HMPREF0216_01847 | Stage II sporulation protein P. | sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.813 |
| EKY22752.1 | EKY26988.1 | HMPREF0216_03116 | HMPREF0216_01591 | Stage II sporulation protein P. | Stage III sporulation protein AA; KEGG: rso:RSc1335 0.0072 clpB; ATP-dependent protease K03695; Psort location: Cytoplasmic, score: 7.50. | 0.854 |
| EKY22752.1 | EKY27009.1 | HMPREF0216_03116 | HMPREF0216_01612 | Stage II sporulation protein P. | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.821 |
| EKY22752.1 | EKY27243.1 | HMPREF0216_03116 | HMPREF0216_01495 | Stage II sporulation protein P. | Stage V sporulation protein T; Psort location: Cytoplasmic, score: 9.97. | 0.778 |
| EKY22752.1 | EKY27642.1 | HMPREF0216_03116 | HMPREF0216_01285 | Stage II sporulation protein P. | Stage II sporulation protein R; Psort location: Cytoplasmic, score: 7.50. | 0.905 |
| EKY22752.1 | EKY27672.1 | HMPREF0216_03116 | HMPREF0216_01315 | Stage II sporulation protein P. | Sporulation transcriptional regulator SpoIIID; Psort location: Cytoplasmic, score: 7.50. | 0.865 |
| EKY22752.1 | spoIIAB | HMPREF0216_03116 | HMPREF0216_03136 | Stage II sporulation protein P. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.888 |
| EKY25257.1 | EKY22752.1 | HMPREF0216_02547 | HMPREF0216_03116 | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | Stage II sporulation protein P. | 0.902 |
| EKY25257.1 | EKY26645.1 | HMPREF0216_02547 | HMPREF0216_01830 | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.828 |
| EKY25257.1 | EKY26660.1 | HMPREF0216_02547 | HMPREF0216_01845 | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.874 |
| EKY25257.1 | EKY26662.1 | HMPREF0216_02547 | HMPREF0216_01847 | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.940 |
| EKY25257.1 | EKY26988.1 | HMPREF0216_02547 | HMPREF0216_01591 | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | Stage III sporulation protein AA; KEGG: rso:RSc1335 0.0072 clpB; ATP-dependent protease K03695; Psort location: Cytoplasmic, score: 7.50. | 0.834 |
| EKY25257.1 | EKY27009.1 | HMPREF0216_02547 | HMPREF0216_01612 | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.888 |
| EKY25257.1 | EKY27243.1 | HMPREF0216_02547 | HMPREF0216_01495 | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | Stage V sporulation protein T; Psort location: Cytoplasmic, score: 9.97. | 0.836 |
| EKY25257.1 | EKY27642.1 | HMPREF0216_02547 | HMPREF0216_01285 | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | Stage II sporulation protein R; Psort location: Cytoplasmic, score: 7.50. | 0.887 |
| EKY25257.1 | EKY27672.1 | HMPREF0216_02547 | HMPREF0216_01315 | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | Sporulation transcriptional regulator SpoIIID; Psort location: Cytoplasmic, score: 7.50. | 0.861 |
| EKY25257.1 | spoIIAB | HMPREF0216_02547 | HMPREF0216_03136 | KEGG: cbe:Cbei_0097 2.2e-181 sporulation stage II, protein E K06382; Psort location: CytoplasmicMembrane, score: 10.00. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.907 |