| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22381.1 | EKY25087.1 | HMPREF0216_03269 | HMPREF0216_02555 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein. | 0.627 |
| EKY22381.1 | EKY28194.1 | HMPREF0216_03269 | HMPREF0216_01038 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Phosphoribulokinase/uridine kinase family protein. | 0.437 |
| EKY22381.1 | guaA | HMPREF0216_03269 | HMPREF0216_03257 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.931 |
| EKY22381.1 | purA | HMPREF0216_03269 | HMPREF0216_00109 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.887 |
| EKY22386.1 | EKY24021.1 | HMPREF0216_03247 | HMPREF0216_02780 | SCP-like protein; KEGG: hau:Haur_4796 0.00066 serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial. | Pullulanase, type I; Belongs to the glycosyl hydrolase 13 family. | 0.479 |
| EKY22386.1 | EKY25087.1 | HMPREF0216_03247 | HMPREF0216_02555 | SCP-like protein; KEGG: hau:Haur_4796 0.00066 serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial. | Hypothetical protein. | 0.626 |
| EKY22386.1 | nadD | HMPREF0216_03247 | HMPREF0216_03301 | SCP-like protein; KEGG: hau:Haur_4796 0.00066 serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.551 |
| EKY24021.1 | EKY22386.1 | HMPREF0216_02780 | HMPREF0216_03247 | Pullulanase, type I; Belongs to the glycosyl hydrolase 13 family. | SCP-like protein; KEGG: hau:Haur_4796 0.00066 serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial. | 0.479 |
| EKY24021.1 | EKY25087.1 | HMPREF0216_02780 | HMPREF0216_02555 | Pullulanase, type I; Belongs to the glycosyl hydrolase 13 family. | Hypothetical protein. | 0.811 |
| EKY24021.1 | EKY29053.1 | HMPREF0216_02780 | HMPREF0216_00412 | Pullulanase, type I; Belongs to the glycosyl hydrolase 13 family. | KEGG: chu:CHU_3450 0.00096 hypothetical protein K01238; Psort location: Cytoplasmic, score: 7.50. | 0.620 |
| EKY24021.1 | guaA | HMPREF0216_02780 | HMPREF0216_03257 | Pullulanase, type I; Belongs to the glycosyl hydrolase 13 family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.432 |
| EKY25087.1 | EKY22381.1 | HMPREF0216_02555 | HMPREF0216_03269 | Hypothetical protein. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.627 |
| EKY25087.1 | EKY22386.1 | HMPREF0216_02555 | HMPREF0216_03247 | Hypothetical protein. | SCP-like protein; KEGG: hau:Haur_4796 0.00066 serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial. | 0.626 |
| EKY25087.1 | EKY24021.1 | HMPREF0216_02555 | HMPREF0216_02780 | Hypothetical protein. | Pullulanase, type I; Belongs to the glycosyl hydrolase 13 family. | 0.811 |
| EKY25087.1 | EKY28078.1 | HMPREF0216_02555 | HMPREF0216_00920 | Hypothetical protein. | Putative phage head-tail adaptor. | 0.595 |
| EKY25087.1 | EKY28194.1 | HMPREF0216_02555 | HMPREF0216_01038 | Hypothetical protein. | Phosphoribulokinase/uridine kinase family protein. | 0.789 |
| EKY25087.1 | EKY29053.1 | HMPREF0216_02555 | HMPREF0216_00412 | Hypothetical protein. | KEGG: chu:CHU_3450 0.00096 hypothetical protein K01238; Psort location: Cytoplasmic, score: 7.50. | 0.587 |
| EKY25087.1 | EKY29460.1 | HMPREF0216_02555 | HMPREF0216_00225 | Hypothetical protein. | DJ-1 family protein; KEGG: gym:GYMC10_1577 4.6e-21 intracellular protease, PfpI family; K05520 protease I; Psort location: Cytoplasmic, score: 7.50. | 0.588 |
| EKY25087.1 | guaA | HMPREF0216_02555 | HMPREF0216_03257 | Hypothetical protein. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.793 |
| EKY25087.1 | nadD | HMPREF0216_02555 | HMPREF0216_03301 | Hypothetical protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.675 |