| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY23231.1 | EKY24605.1 | HMPREF0216_03016 | HMPREF0216_02635 | Putative nitrite transporter NirC; KEGG: bcz:BCZK3485 2.3e-28 fdhC; formate transporter K00122; Psort location: CytoplasmicMembrane, score: 10.00. | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | 0.665 |
| EKY24605.1 | EKY23231.1 | HMPREF0216_02635 | HMPREF0216_03016 | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | Putative nitrite transporter NirC; KEGG: bcz:BCZK3485 2.3e-28 fdhC; formate transporter K00122; Psort location: CytoplasmicMembrane, score: 10.00. | 0.665 |
| EKY24605.1 | EKY26267.1 | HMPREF0216_02635 | HMPREF0216_02049 | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | Bacterial transferase hexapeptide repeat protein; KEGG: hse:Hsero_1727 1.2e-38 carbonic anhydrase/acetyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.948 |
| EKY24605.1 | EKY28590.1 | HMPREF0216_02635 | HMPREF0216_00643 | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | KEGG: cpr:CPR_2286 8.0e-175 bcd; butyryl-CoA dehydrogenase K00248; Psort location: Cytoplasmic, score: 9.97. | 0.440 |
| EKY24605.1 | EKY29671.1 | HMPREF0216_02635 | HMPREF0216_00079 | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | KEGG: cbe:Cbei_2798 3.9e-88 phosphoglycerate mutase; K01834 phosphoglycerate mutase; Psort location: Cytoplasmic, score: 7.50. | 0.975 |
| EKY24605.1 | guaB | HMPREF0216_02635 | HMPREF0216_03256 | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.431 |
| EKY24605.1 | ureA | HMPREF0216_02635 | HMPREF0216_02636 | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | Urease, gamma subunit; KEGG: ach:Achl_0390 8.6e-36 ureA; urease subunit gamma K01430; Psort location: Cytoplasmic, score: 9.97. | 0.509 |
| EKY24605.1 | ureB | HMPREF0216_02635 | HMPREF0216_02637 | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | Urease, beta subunit; KEGG: aau:AAur_0215 1.5e-31 ureB; urease, beta subunit K01429; Psort location: Cytoplasmic, score: 9.67. | 0.482 |
| EKY24605.1 | ureC | HMPREF0216_02635 | HMPREF0216_02638 | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | Urease, alpha subunit; KEGG: cpy:Cphy_0687 3.5e-213 ureC; urease subunit alpha; K01428 urease subunit alpha; Psort location: Cytoplasmic, score: 9.97. | 0.482 |
| EKY24605.1 | ureE | HMPREF0216_02635 | HMPREF0216_02639 | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | Urease accessory protein UreE domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.459 |
| EKY24605.1 | ureF | HMPREF0216_02635 | HMPREF0216_02640 | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.459 |
| EKY26267.1 | EKY24605.1 | HMPREF0216_02049 | HMPREF0216_02635 | Bacterial transferase hexapeptide repeat protein; KEGG: hse:Hsero_1727 1.2e-38 carbonic anhydrase/acetyltransferase; Psort location: Cytoplasmic, score: 7.50. | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | 0.948 |
| EKY28590.1 | EKY24605.1 | HMPREF0216_00643 | HMPREF0216_02635 | KEGG: cpr:CPR_2286 8.0e-175 bcd; butyryl-CoA dehydrogenase K00248; Psort location: Cytoplasmic, score: 9.97. | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | 0.440 |
| EKY29671.1 | EKY24605.1 | HMPREF0216_00079 | HMPREF0216_02635 | KEGG: cbe:Cbei_2798 3.9e-88 phosphoglycerate mutase; K01834 phosphoglycerate mutase; Psort location: Cytoplasmic, score: 7.50. | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | 0.975 |
| guaB | EKY24605.1 | HMPREF0216_03256 | HMPREF0216_02635 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | 0.431 |
| ureA | EKY24605.1 | HMPREF0216_02636 | HMPREF0216_02635 | Urease, gamma subunit; KEGG: ach:Achl_0390 8.6e-36 ureA; urease subunit gamma K01430; Psort location: Cytoplasmic, score: 9.97. | Carbonate dehydratase; KEGG: tjr:TherJR_0949 5.5e-41 carbonic anhydrase; K01673 carbonic anhydrase; Psort location: Cytoplasmic, score: 9.67. | 0.509 |
| ureA | ureB | HMPREF0216_02636 | HMPREF0216_02637 | Urease, gamma subunit; KEGG: ach:Achl_0390 8.6e-36 ureA; urease subunit gamma K01430; Psort location: Cytoplasmic, score: 9.97. | Urease, beta subunit; KEGG: aau:AAur_0215 1.5e-31 ureB; urease, beta subunit K01429; Psort location: Cytoplasmic, score: 9.67. | 0.999 |
| ureA | ureC | HMPREF0216_02636 | HMPREF0216_02638 | Urease, gamma subunit; KEGG: ach:Achl_0390 8.6e-36 ureA; urease subunit gamma K01430; Psort location: Cytoplasmic, score: 9.97. | Urease, alpha subunit; KEGG: cpy:Cphy_0687 3.5e-213 ureC; urease subunit alpha; K01428 urease subunit alpha; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
| ureA | ureE | HMPREF0216_02636 | HMPREF0216_02639 | Urease, gamma subunit; KEGG: ach:Achl_0390 8.6e-36 ureA; urease subunit gamma K01430; Psort location: Cytoplasmic, score: 9.97. | Urease accessory protein UreE domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.990 |
| ureA | ureF | HMPREF0216_02636 | HMPREF0216_02640 | Urease, gamma subunit; KEGG: ach:Achl_0390 8.6e-36 ureA; urease subunit gamma K01430; Psort location: Cytoplasmic, score: 9.97. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.994 |