Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
larCTIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (436 aa)    
Predicted Functional Partners:
EKY24458.1
Hypothetical protein; KEGG: sat:SYN_00474 7.9e-65 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K06898.
 
  
 0.985
EKY24460.1
TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50.
  
 0.970
EKY24457.1
Oxidoreductase, aldo/keto reductase family protein; KEGG: ava:Ava_1414 2.6e-14 aldo/keto reductase; K05885 2,5-diketo-D-gluconate reductase K07079; Psort location: Cytoplasmic, score: 7.50.
 
    0.610
EKY27130.1
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 8.1e-24 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family.
       0.487
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
       0.469
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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