| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY24457.1 | EKY24458.1 | HMPREF0216_02680 | HMPREF0216_02681 | Oxidoreductase, aldo/keto reductase family protein; KEGG: ava:Ava_1414 2.6e-14 aldo/keto reductase; K05885 2,5-diketo-D-gluconate reductase K07079; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: sat:SYN_00474 7.9e-65 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K06898. | 0.616 |
| EKY24457.1 | EKY24460.1 | HMPREF0216_02680 | HMPREF0216_02683 | Oxidoreductase, aldo/keto reductase family protein; KEGG: ava:Ava_1414 2.6e-14 aldo/keto reductase; K05885 2,5-diketo-D-gluconate reductase K07079; Psort location: Cytoplasmic, score: 7.50. | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | 0.616 |
| EKY24457.1 | larC | HMPREF0216_02680 | HMPREF0216_02682 | Oxidoreductase, aldo/keto reductase family protein; KEGG: ava:Ava_1414 2.6e-14 aldo/keto reductase; K05885 2,5-diketo-D-gluconate reductase K07079; Psort location: Cytoplasmic, score: 7.50. | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | 0.632 |
| EKY24458.1 | EKY24457.1 | HMPREF0216_02681 | HMPREF0216_02680 | Hypothetical protein; KEGG: sat:SYN_00474 7.9e-65 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K06898. | Oxidoreductase, aldo/keto reductase family protein; KEGG: ava:Ava_1414 2.6e-14 aldo/keto reductase; K05885 2,5-diketo-D-gluconate reductase K07079; Psort location: Cytoplasmic, score: 7.50. | 0.616 |
| EKY24458.1 | EKY24460.1 | HMPREF0216_02681 | HMPREF0216_02683 | Hypothetical protein; KEGG: sat:SYN_00474 7.9e-65 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K06898. | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | 0.979 |
| EKY24458.1 | larC | HMPREF0216_02681 | HMPREF0216_02682 | Hypothetical protein; KEGG: sat:SYN_00474 7.9e-65 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K06898. | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | 0.982 |
| EKY24460.1 | EKY24457.1 | HMPREF0216_02683 | HMPREF0216_02680 | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | Oxidoreductase, aldo/keto reductase family protein; KEGG: ava:Ava_1414 2.6e-14 aldo/keto reductase; K05885 2,5-diketo-D-gluconate reductase K07079; Psort location: Cytoplasmic, score: 7.50. | 0.616 |
| EKY24460.1 | EKY24458.1 | HMPREF0216_02683 | HMPREF0216_02681 | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: sat:SYN_00474 7.9e-65 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K06898. | 0.979 |
| EKY24460.1 | EKY24461.1 | HMPREF0216_02683 | HMPREF0216_02684 | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | 4Fe-4S binding domain protein; KEGG: lbi:LEPBI_I2457 5.8e-14 putative thioredoxin-disulfide reductase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.524 |
| EKY24460.1 | EKY27368.1 | HMPREF0216_02683 | HMPREF0216_01401 | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | PP-loop family protein; KEGG: fbl:Fbal_1913 2.1e-32 tRNA s(2)C-32 sulfurtransferase; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.503 |
| EKY24460.1 | EKY27751.1 | HMPREF0216_02683 | HMPREF0216_01225 | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | Hydrolase, haloacid dehalogenase-like family protein; KEGG: hiq:CGSHiGG_02755 1.4e-53 glucuronate isomerase; Psort location: Cytoplasmic, score: 7.50. | 0.432 |
| EKY24460.1 | larC | HMPREF0216_02683 | HMPREF0216_02682 | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | 0.969 |
| EKY24460.1 | nth | HMPREF0216_02683 | HMPREF0216_01011 | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.690 |
| EKY24461.1 | EKY24460.1 | HMPREF0216_02684 | HMPREF0216_02683 | 4Fe-4S binding domain protein; KEGG: lbi:LEPBI_I2457 5.8e-14 putative thioredoxin-disulfide reductase; Psort location: CytoplasmicMembrane, score: 10.00. | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | 0.524 |
| EKY27368.1 | EKY24460.1 | HMPREF0216_01401 | HMPREF0216_02683 | PP-loop family protein; KEGG: fbl:Fbal_1913 2.1e-32 tRNA s(2)C-32 sulfurtransferase; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | 0.503 |
| EKY27751.1 | EKY24460.1 | HMPREF0216_01225 | HMPREF0216_02683 | Hydrolase, haloacid dehalogenase-like family protein; KEGG: hiq:CGSHiGG_02755 1.4e-53 glucuronate isomerase; Psort location: Cytoplasmic, score: 7.50. | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | 0.432 |
| larC | EKY24457.1 | HMPREF0216_02682 | HMPREF0216_02680 | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | Oxidoreductase, aldo/keto reductase family protein; KEGG: ava:Ava_1414 2.6e-14 aldo/keto reductase; K05885 2,5-diketo-D-gluconate reductase K07079; Psort location: Cytoplasmic, score: 7.50. | 0.632 |
| larC | EKY24458.1 | HMPREF0216_02682 | HMPREF0216_02681 | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | Hypothetical protein; KEGG: sat:SYN_00474 7.9e-65 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K06898. | 0.982 |
| larC | EKY24460.1 | HMPREF0216_02682 | HMPREF0216_02683 | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | 0.969 |
| nth | EKY24460.1 | HMPREF0216_01011 | HMPREF0216_02683 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | TIGR00268 family protein; KEGG: pmc:P9515_17581 3.9e-47 PP family ATPase K06864; Psort location: Cytoplasmic, score: 7.50. | 0.690 |