| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY23482.1 | EKY23867.1 | HMPREF0216_02918 | HMPREF0216_02880 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.819 |
| EKY23482.1 | EKY24627.1 | HMPREF0216_02918 | HMPREF0216_02657 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | KEGG: cth:Cthe_1217 1.1e-207 ATP-dependent Clp protease ATP-binding subunit ClpA K03694; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | 0.493 |
| EKY23482.1 | EKY25601.1 | HMPREF0216_02918 | HMPREF0216_02421 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbl:CLK_2956 8.8e-272 clpC; negative regulator of genetic competence MecB/ClpC K03696; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | 0.493 |
| EKY23482.1 | clpB | HMPREF0216_02918 | HMPREF0216_02599 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.493 |
| EKY23482.1 | groL | HMPREF0216_02918 | HMPREF0216_00566 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.542 |
| EKY23482.1 | grpE | HMPREF0216_02918 | HMPREF0216_03110 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.694 |
| EKY23482.1 | htpG | HMPREF0216_02918 | HMPREF0216_03409 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.844 |
| EKY23867.1 | EKY23482.1 | HMPREF0216_02880 | HMPREF0216_02918 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | 0.819 |
| EKY23867.1 | EKY23868.1 | HMPREF0216_02880 | HMPREF0216_02881 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein. | 0.773 |
| EKY23867.1 | EKY24627.1 | HMPREF0216_02880 | HMPREF0216_02657 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | KEGG: cth:Cthe_1217 1.1e-207 ATP-dependent Clp protease ATP-binding subunit ClpA K03694; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | 0.783 |
| EKY23867.1 | EKY25601.1 | HMPREF0216_02880 | HMPREF0216_02421 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbl:CLK_2956 8.8e-272 clpC; negative regulator of genetic competence MecB/ClpC K03696; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | 0.783 |
| EKY23867.1 | EKY28795.1 | HMPREF0216_02880 | HMPREF0216_00567 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.847 |
| EKY23867.1 | clpB | HMPREF0216_02880 | HMPREF0216_02599 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.783 |
| EKY23867.1 | groL | HMPREF0216_02880 | HMPREF0216_00566 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.896 |
| EKY23867.1 | grpE | HMPREF0216_02880 | HMPREF0216_03110 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.934 |
| EKY23867.1 | htpG | HMPREF0216_02880 | HMPREF0216_03409 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.916 |
| EKY23867.1 | rplP | HMPREF0216_02880 | HMPREF0216_01158 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.787 |
| EKY23868.1 | EKY23867.1 | HMPREF0216_02881 | HMPREF0216_02880 | Hypothetical protein. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.773 |
| EKY24627.1 | EKY23482.1 | HMPREF0216_02657 | HMPREF0216_02918 | KEGG: cth:Cthe_1217 1.1e-207 ATP-dependent Clp protease ATP-binding subunit ClpA K03694; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | 0.493 |
| EKY24627.1 | EKY23867.1 | HMPREF0216_02657 | HMPREF0216_02880 | KEGG: cth:Cthe_1217 1.1e-207 ATP-dependent Clp protease ATP-binding subunit ClpA K03694; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.783 |