Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
hemLGlutamate-1-semialdehyde-2,1-aminomutase; KEGG: cpf:CPF_1685 2.1e-174 hemL; glutamate-1-semialdehyde aminotransferase K01845; Psort location: Cytoplasmic, score: 9.97. (424 aa)    
Predicted Functional Partners:
EKY23235.1
Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family.
 
 
 0.996
EKY23236.1
KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.996
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.993
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.976
EKY23238.1
KEGG: clj:CLJU_c31990 2.5e-36 sirC; precorrin-2 dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.902
EKY22237.1
Condensation domain protein; KEGG: ppy:PPE_00083 2.2e-20 bacitracin synthetase 3; Psort location: Cytoplasmic, score: 7.50.
     
 0.772
EKY23233.1
Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50.
 
     0.751
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.698
EKY28426.1
Class II glutamine amidotransferase.
     
 0.657
EKY27893.1
Cytochrome C biogenesis protein transmembrane region; KEGG: dat:HRM2_42210 2.8e-37 dsbD; DsbD K06196; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.639
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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