| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22237.1 | EKY23235.1 | HMPREF0216_03281 | HMPREF0216_03020 | Condensation domain protein; KEGG: ppy:PPE_00083 2.2e-20 bacitracin synthetase 3; Psort location: Cytoplasmic, score: 7.50. | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | 0.813 |
| EKY22237.1 | hemL | HMPREF0216_03281 | HMPREF0216_03019 | Condensation domain protein; KEGG: ppy:PPE_00083 2.2e-20 bacitracin synthetase 3; Psort location: Cytoplasmic, score: 7.50. | Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: cpf:CPF_1685 2.1e-174 hemL; glutamate-1-semialdehyde aminotransferase K01845; Psort location: Cytoplasmic, score: 9.97. | 0.988 |
| EKY23233.1 | EKY23235.1 | HMPREF0216_03018 | HMPREF0216_03020 | Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50. | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | 0.821 |
| EKY23233.1 | EKY23236.1 | HMPREF0216_03018 | HMPREF0216_03021 | Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50. | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | 0.977 |
| EKY23233.1 | EKY23238.1 | HMPREF0216_03018 | HMPREF0216_03023 | Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50. | KEGG: clj:CLJU_c31990 2.5e-36 sirC; precorrin-2 dehydrogenase; Psort location: Cytoplasmic, score: 7.50. | 0.930 |
| EKY23233.1 | EKY25834.1 | HMPREF0216_03018 | HMPREF0216_02320 | Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50. | KEGG: cpe:CPE1040 7.5e-108 threonine-phosphate decarboxylase K04720. | 0.745 |
| EKY23233.1 | cbiA | HMPREF0216_03018 | HMPREF0216_03179 | Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.847 |
| EKY23233.1 | hemA | HMPREF0216_03018 | HMPREF0216_03024 | Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.660 |
| EKY23233.1 | hemC | HMPREF0216_03018 | HMPREF0216_03022 | Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.751 |
| EKY23233.1 | hemL | HMPREF0216_03018 | HMPREF0216_03019 | Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50. | Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: cpf:CPF_1685 2.1e-174 hemL; glutamate-1-semialdehyde aminotransferase K01845; Psort location: Cytoplasmic, score: 9.97. | 0.759 |
| EKY23235.1 | EKY22237.1 | HMPREF0216_03020 | HMPREF0216_03281 | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Condensation domain protein; KEGG: ppy:PPE_00083 2.2e-20 bacitracin synthetase 3; Psort location: Cytoplasmic, score: 7.50. | 0.813 |
| EKY23235.1 | EKY23233.1 | HMPREF0216_03020 | HMPREF0216_03018 | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50. | 0.821 |
| EKY23235.1 | EKY23236.1 | HMPREF0216_03020 | HMPREF0216_03021 | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50. | 0.999 |
| EKY23235.1 | EKY23238.1 | HMPREF0216_03020 | HMPREF0216_03023 | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | KEGG: clj:CLJU_c31990 2.5e-36 sirC; precorrin-2 dehydrogenase; Psort location: Cytoplasmic, score: 7.50. | 0.851 |
| EKY23235.1 | EKY25834.1 | HMPREF0216_03020 | HMPREF0216_02320 | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | KEGG: cpe:CPE1040 7.5e-108 threonine-phosphate decarboxylase K04720. | 0.564 |
| EKY23235.1 | cbiA | HMPREF0216_03020 | HMPREF0216_03179 | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.579 |
| EKY23235.1 | hemA | HMPREF0216_03020 | HMPREF0216_03024 | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.957 |
| EKY23235.1 | hemC | HMPREF0216_03020 | HMPREF0216_03022 | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
| EKY23235.1 | hemL | HMPREF0216_03020 | HMPREF0216_03019 | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: cpf:CPF_1685 2.1e-174 hemL; glutamate-1-semialdehyde aminotransferase K01845; Psort location: Cytoplasmic, score: 9.97. | 0.997 |
| EKY23235.1 | ribBA | HMPREF0216_03020 | HMPREF0216_00786 | Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.635 |