STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (289 aa)    
Predicted Functional Partners:
EKY23236.1
KEGG: cpr:CPR_1421 1.6e-178 hemD; uroporphyrinogen-III methyltransferase/synthase K13542; Psort location: Cytoplasmic, score: 7.50.
 0.999
EKY23235.1
Porphobilinogen synthase; KEGG: ctc:CTC00729 1.1e-124 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family.
 
 0.998
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.994
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: cpf:CPF_1685 2.1e-174 hemL; glutamate-1-semialdehyde aminotransferase K01845; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.977
EKY23238.1
KEGG: clj:CLJU_c31990 2.5e-36 sirC; precorrin-2 dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.936
EKY23233.1
Cobalt chelatase; KEGG: cpr:CPR_1242 9.9e-35 anaerobic cobalt chelatase, CbiK; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.751
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
   
 0.568
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
   
    0.555
EKY25834.1
KEGG: cpe:CPE1040 7.5e-108 threonine-phosphate decarboxylase K04720.
 
  
 0.544
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.517
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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