| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22734.1 | EKY22735.1 | HMPREF0216_03098 | HMPREF0216_03099 | KEGG: rno:690660 5.2e-29 Hint1, Pkci, Prkci; histidine triad nucleotide binding protein 1. | tRNA methylthiotransferase YqeV; KEGG: ctc:CTC02027 4.3e-144 Fe-S oxidoreductase K03423; Psort location: Cytoplasmic, score: 7.50. | 0.659 |
| EKY22734.1 | EKY22736.1 | HMPREF0216_03098 | HMPREF0216_03100 | KEGG: rno:690660 5.2e-29 Hint1, Pkci, Prkci; histidine triad nucleotide binding protein 1. | RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.626 |
| EKY22734.1 | EKY23482.1 | HMPREF0216_03098 | HMPREF0216_02918 | KEGG: rno:690660 5.2e-29 Hint1, Pkci, Prkci; histidine triad nucleotide binding protein 1. | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | 0.747 |
| EKY22734.1 | dnaJ | HMPREF0216_03098 | HMPREF0216_03106 | KEGG: rno:690660 5.2e-29 Hint1, Pkci, Prkci; histidine triad nucleotide binding protein 1. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.462 |
| EKY22734.1 | era | HMPREF0216_03098 | HMPREF0216_03088 | KEGG: rno:690660 5.2e-29 Hint1, Pkci, Prkci; histidine triad nucleotide binding protein 1. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.433 |
| EKY22734.1 | prmA | HMPREF0216_03098 | HMPREF0216_03101 | KEGG: rno:690660 5.2e-29 Hint1, Pkci, Prkci; histidine triad nucleotide binding protein 1. | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.596 |
| EKY22734.1 | rpsU | HMPREF0216_03098 | HMPREF0216_03097 | KEGG: rno:690660 5.2e-29 Hint1, Pkci, Prkci; histidine triad nucleotide binding protein 1. | Ribosomal protein S21; KEGG: sew:SeSA_A3399 6.0e-12 rpsU; 30S ribosomal protein S21 K02970; Psort location: Cytoplasmic, score: 9.97; Belongs to the bacterial ribosomal protein bS21 family. | 0.638 |
| EKY22734.1 | ybeY | HMPREF0216_03098 | HMPREF0216_03091 | KEGG: rno:690660 5.2e-29 Hint1, Pkci, Prkci; histidine triad nucleotide binding protein 1. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.533 |
| EKY22735.1 | EKY22734.1 | HMPREF0216_03099 | HMPREF0216_03098 | tRNA methylthiotransferase YqeV; KEGG: ctc:CTC02027 4.3e-144 Fe-S oxidoreductase K03423; Psort location: Cytoplasmic, score: 7.50. | KEGG: rno:690660 5.2e-29 Hint1, Pkci, Prkci; histidine triad nucleotide binding protein 1. | 0.659 |
| EKY22735.1 | EKY22736.1 | HMPREF0216_03099 | HMPREF0216_03100 | tRNA methylthiotransferase YqeV; KEGG: ctc:CTC02027 4.3e-144 Fe-S oxidoreductase K03423; Psort location: Cytoplasmic, score: 7.50. | RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.899 |
| EKY22735.1 | EKY26149.1 | HMPREF0216_03099 | HMPREF0216_02188 | tRNA methylthiotransferase YqeV; KEGG: ctc:CTC02027 4.3e-144 Fe-S oxidoreductase K03423; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbk:CLL_A0983 3.9e-88 prmA; ribosomal protein L11 methyltransferase K02687. | 0.507 |
| EKY22735.1 | EKY26632.1 | HMPREF0216_03099 | HMPREF0216_01817 | tRNA methylthiotransferase YqeV; KEGG: ctc:CTC02027 4.3e-144 Fe-S oxidoreductase K03423; Psort location: Cytoplasmic, score: 7.50. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.642 |
| EKY22735.1 | dnaJ | HMPREF0216_03099 | HMPREF0216_03106 | tRNA methylthiotransferase YqeV; KEGG: ctc:CTC02027 4.3e-144 Fe-S oxidoreductase K03423; Psort location: Cytoplasmic, score: 7.50. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.475 |
| EKY22735.1 | era | HMPREF0216_03099 | HMPREF0216_03088 | tRNA methylthiotransferase YqeV; KEGG: ctc:CTC02027 4.3e-144 Fe-S oxidoreductase K03423; Psort location: Cytoplasmic, score: 7.50. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.428 |
| EKY22735.1 | prmA | HMPREF0216_03099 | HMPREF0216_03101 | tRNA methylthiotransferase YqeV; KEGG: ctc:CTC02027 4.3e-144 Fe-S oxidoreductase K03423; Psort location: Cytoplasmic, score: 7.50. | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.883 |
| EKY22735.1 | rpsU | HMPREF0216_03099 | HMPREF0216_03097 | tRNA methylthiotransferase YqeV; KEGG: ctc:CTC02027 4.3e-144 Fe-S oxidoreductase K03423; Psort location: Cytoplasmic, score: 7.50. | Ribosomal protein S21; KEGG: sew:SeSA_A3399 6.0e-12 rpsU; 30S ribosomal protein S21 K02970; Psort location: Cytoplasmic, score: 9.97; Belongs to the bacterial ribosomal protein bS21 family. | 0.552 |
| EKY22736.1 | EKY22734.1 | HMPREF0216_03100 | HMPREF0216_03098 | RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | KEGG: rno:690660 5.2e-29 Hint1, Pkci, Prkci; histidine triad nucleotide binding protein 1. | 0.626 |
| EKY22736.1 | EKY22735.1 | HMPREF0216_03100 | HMPREF0216_03099 | RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | tRNA methylthiotransferase YqeV; KEGG: ctc:CTC02027 4.3e-144 Fe-S oxidoreductase K03423; Psort location: Cytoplasmic, score: 7.50. | 0.899 |
| EKY22736.1 | EKY23482.1 | HMPREF0216_03100 | HMPREF0216_02918 | RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 5.1e-10 TPR repeat-containing serine/threonin protein kinase K00908; Psort location: Cytoplasmic, score: 7.50. | 0.510 |
| EKY22736.1 | EKY26149.1 | HMPREF0216_03100 | HMPREF0216_02188 | RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | KEGG: cbk:CLL_A0983 3.9e-88 prmA; ribosomal protein L11 methyltransferase K02687. | 0.580 |