| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22379.1 | EKY22381.1 | HMPREF0216_03267 | HMPREF0216_03269 | Hypothetical protein; KEGG: pfd:PFDG_01700 1.2e-05 hypothetical protein similar to prolyl-t-RNA synthase; K01881 prolyl-tRNA synthetase. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.625 |
| EKY22379.1 | EKY22382.1 | HMPREF0216_03267 | HMPREF0216_03270 | Hypothetical protein; KEGG: pfd:PFDG_01700 1.2e-05 hypothetical protein similar to prolyl-t-RNA synthase; K01881 prolyl-tRNA synthetase. | KEGG: cbk:CLL_A0419 2.3e-42 phosphodiesterase, family K07095. | 0.496 |
| EKY22379.1 | rph | HMPREF0216_03267 | HMPREF0216_03268 | Hypothetical protein; KEGG: pfd:PFDG_01700 1.2e-05 hypothetical protein similar to prolyl-t-RNA synthase; K01881 prolyl-tRNA synthetase. | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.543 |
| EKY22381.1 | EKY22379.1 | HMPREF0216_03269 | HMPREF0216_03267 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein; KEGG: pfd:PFDG_01700 1.2e-05 hypothetical protein similar to prolyl-t-RNA synthase; K01881 prolyl-tRNA synthetase. | 0.625 |
| EKY22381.1 | EKY22382.1 | HMPREF0216_03269 | HMPREF0216_03270 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | KEGG: cbk:CLL_A0419 2.3e-42 phosphodiesterase, family K07095. | 0.849 |
| EKY22381.1 | rph | HMPREF0216_03269 | HMPREF0216_03268 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.993 |
| EKY22382.1 | EKY22379.1 | HMPREF0216_03270 | HMPREF0216_03267 | KEGG: cbk:CLL_A0419 2.3e-42 phosphodiesterase, family K07095. | Hypothetical protein; KEGG: pfd:PFDG_01700 1.2e-05 hypothetical protein similar to prolyl-t-RNA synthase; K01881 prolyl-tRNA synthetase. | 0.496 |
| EKY22382.1 | EKY22381.1 | HMPREF0216_03270 | HMPREF0216_03269 | KEGG: cbk:CLL_A0419 2.3e-42 phosphodiesterase, family K07095. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.849 |
| EKY22382.1 | rph | HMPREF0216_03270 | HMPREF0216_03268 | KEGG: cbk:CLL_A0419 2.3e-42 phosphodiesterase, family K07095. | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.635 |
| rph | EKY22379.1 | HMPREF0216_03268 | HMPREF0216_03267 | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Hypothetical protein; KEGG: pfd:PFDG_01700 1.2e-05 hypothetical protein similar to prolyl-t-RNA synthase; K01881 prolyl-tRNA synthetase. | 0.543 |
| rph | EKY22381.1 | HMPREF0216_03268 | HMPREF0216_03269 | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.993 |
| rph | EKY22382.1 | HMPREF0216_03268 | HMPREF0216_03270 | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | KEGG: cbk:CLL_A0419 2.3e-42 phosphodiesterase, family K07095. | 0.635 |
