| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22256.1 | EKY22258.1 | HMPREF0216_03300 | HMPREF0216_03302 | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 7.50. | 0.893 |
| EKY22256.1 | EKY25789.1 | HMPREF0216_03300 | HMPREF0216_02371 | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein. | 0.745 |
| EKY22256.1 | EKY26087.1 | HMPREF0216_03300 | HMPREF0216_02126 | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.745 |
| EKY22256.1 | EKY27130.1 | HMPREF0216_03300 | HMPREF0216_01541 | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 8.1e-24 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family. | 0.851 |
| EKY22256.1 | nadD | HMPREF0216_03300 | HMPREF0216_03301 | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.998 |
| EKY22256.1 | nadE | HMPREF0216_03300 | HMPREF0216_02039 | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.870 |
| EKY22256.1 | nadK | HMPREF0216_03300 | HMPREF0216_01608 | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Inorganic polyphosphate/ATP-NAD kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.818 |
| EKY22256.1 | obg | HMPREF0216_03300 | HMPREF0216_03303 | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.841 |
| EKY22258.1 | EKY22256.1 | HMPREF0216_03302 | HMPREF0216_03300 | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 7.50. | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.893 |
| EKY22258.1 | nadD | HMPREF0216_03302 | HMPREF0216_03301 | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 7.50. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.945 |
| EKY22258.1 | obg | HMPREF0216_03302 | HMPREF0216_03303 | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 7.50. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.849 |
| EKY25789.1 | EKY22256.1 | HMPREF0216_02371 | HMPREF0216_03300 | Hypothetical protein. | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.745 |
| EKY25789.1 | EKY27130.1 | HMPREF0216_02371 | HMPREF0216_01541 | Hypothetical protein. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 8.1e-24 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family. | 0.894 |
| EKY25789.1 | EKY29580.1 | HMPREF0216_02371 | HMPREF0216_00163 | Hypothetical protein. | KEGG: cdc:CD196_2211 1.8e-83 nadC; nicotinate-nucleotide pyrophosphorylase; K00767 nicotinate-nucleotide pyrophosphorylase (carboxylating); Psort location: Cytoplasmic, score: 9.67; Belongs to the NadC/ModD family. | 0.879 |
| EKY25789.1 | cobB | HMPREF0216_02371 | HMPREF0216_00506 | Hypothetical protein. | Putative NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.509 |
| EKY25789.1 | nadD | HMPREF0216_02371 | HMPREF0216_03301 | Hypothetical protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.849 |
| EKY25789.1 | nadE | HMPREF0216_02371 | HMPREF0216_02039 | Hypothetical protein. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.688 |
| EKY26087.1 | EKY22256.1 | HMPREF0216_02126 | HMPREF0216_03300 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hydrolase, HD family; KEGG: emi:Emin_0894 7.3e-23 nadD; putative nicotinate-nucleotide adenylyltransferase; K00969 nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.745 |
| EKY26087.1 | EKY27130.1 | HMPREF0216_02126 | HMPREF0216_01541 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 8.1e-24 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family. | 0.894 |
| EKY26087.1 | EKY29580.1 | HMPREF0216_02126 | HMPREF0216_00163 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | KEGG: cdc:CD196_2211 1.8e-83 nadC; nicotinate-nucleotide pyrophosphorylase; K00767 nicotinate-nucleotide pyrophosphorylase (carboxylating); Psort location: Cytoplasmic, score: 9.67; Belongs to the NadC/ModD family. | 0.879 |