Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (216 aa)    
Predicted Functional Partners:
EKY22271.1
KEGG: ava:Ava_3478 1.1e-69 septum site-determining protein MinD K03609; Psort location: CytoplasmicMembrane, score: 8.78.
 
 
 0.999
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
 
  
 0.948
EKY22276.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.946
EKY22275.1
Rod shape-determining protein MreD; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.941
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.901
sepF
Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
  
 0.659
EKY22277.1
KEGG: apb:SAR116_0710 9.8e-99 cell shape determining protein MreB/Mrl K03569; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.659
EKY22263.1
S1 RNA binding domain protein; KEGG: cbe:Cbei_0507 2.2e-140 ribonuclease; K08301 ribonuclease G; Psort location: Cytoplasmic, score: 9.97.
     
 0.590
EKY22278.1
KEGG: apb:SAR116_0666 1.5e-22 DNA repair protein RadC K03630; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0758 family.
  
  
 0.571
EKY22279.1
Maf-like protein; KEGG: apb:SAR116_1315 2.7e-09 nucleotide-binding protein implicated in inhibition of septum formation K06287; Psort location: Cytoplasmic, score: 7.50; Belongs to the Maf family.
  
  
 0.560
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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