Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EKY22287.1MutS domain V protein; KEGG: btk:BT9727_3510 2.3e-15 mutS; DNA mismatch repair protein MutS K03555; Psort location: CytoplasmicMembrane, score: 10.00. (596 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
 0.942
EKY22286.1
Exonuclease; KEGG: bce:BC3538 3.5e-09 exonuclease; Psort location: Cytoplasmic, score: 7.50.
 
    0.843
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.827
EKY22289.1
Ser/Thr phosphatase family protein; KEGG: sax:USA300HOU_1836 2.0e-29 sbcD; DNA repair exonuclease; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.760
EKY27305.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.751
EKY22288.1
Phage tail component protein; KEGG: fnu:FN0522 3.7e-32 exonuclease SBCC K03546; Psort location: Cytoplasmic, score: 7.50.
       0.664
EKY22285.1
CBS domain protein; KEGG: phe:Phep_1434 1.7e-05 cysteine synthase; K01697 cystathionine beta-synthase; Psort location: Cytoplasmic, score: 7.50.
       0.568
EKY28185.1
ATP-dependent DNA helicase RecQ.
   
 0.561
EKY22199.1
KEGG: cpe:CPE0343 1.2e-217 recQ; ATP-dependent DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ; Psort location: Cytoplasmic, score: 9.89.
   
 0.561
dinB
ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.534
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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