Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (391 aa)    
Predicted Functional Partners:
EKY27387.1
Hypothetical protein.
   
 0.947
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.939
EKY26110.1
KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.918
EKY26107.1
KEGG: cbb:CLD_2935 5.6e-103 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.880
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.841
EKY28519.1
KEGG: cno:NT01CX_1210 7.0e-160 O-acetylhomoserine/O-acetylserine sulfhydrylase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.67.
   
 
 0.840
EKY24038.1
DNA-binding helix-turn-helix protein.
    
 0.800
EKY22075.1
Methyltransferase domain protein; KEGG: mma:MM_1949 1.4e-17 methyltransferase; K00599; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.799
EKY26344.1
Aldehyde-alcohol dehydrogenase; KEGG: cbt:CLH_1998 0. bifunctional acetaldehyde-CoA/alcohol dehydrogenase K04072; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 
 0.789
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.758
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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