STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEZ71638.1Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1201 aa)    
Predicted Functional Partners:
putP
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.983
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.983
glnA
Glutamine synthetase, type I; KEGG: nme:NMB0359 1.7e-255 glutamate--ammonia ligase K01915; Psort location: Cytoplasmic, score: 9.26.
   
 
 0.971
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
     
 0.969
lpdA
Dihydrolipoyl dehydrogenase; KEGG: nma:NMA1556 0. lpdA; dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) K00382; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.966
EEZ71149.1
Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; KEGG: nma:NMA1964 3.3e-236 gdhA; glutamate dehydrogenase K00262; Psort location: Cytoplasmic, score: 9.26; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.966
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.961
gltX
glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
    
  0.939
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
  0.938
EEZ72393.1
Dihydrolipoyl dehydrogenase; KEGG: nma:NMA1142 6.0e-244 lpdA2; putative dihydrolipoamide dehydrogenase K00382; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.936
Your Current Organism:
Neisseria cinerea
NCBI taxonomy Id: 546262
Other names: N. cinerea ATCC 14685, Neisseria cinerea ATCC 14685, Neisseria cinerea str. ATCC 14685, Neisseria cinerea strain ATCC 14685
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.