STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plsYAcyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (203 aa)    
Predicted Functional Partners:
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
   
 0.855
gpsA
KEGG: nme:NMB2060 5.6e-154 glycerol-3-phosphate dehydrogenase (NAD(P)+) K00057; Psort location: Cytoplasmic, score: 8.96; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.830
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.765
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
    0.650
EFC87301.1
Acyltransferase; KEGG: ngo:NGO2069 2.9e-109 NlaB K00655.
  
 
 0.646
EFC89797.1
Acyltransferase; KEGG: ngo:NGO0611 4.4e-90 1-acyl-SN-glycerol-3-phosphate acyltransferase K00655; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
  
 
 0.551
EFC89834.1
Acyltransferase; KEGG: eba:ebA5567 1.7e-33 plsC; putative 1-acylglycerol-3-phosphate O-acyltransferase K00655.
  
 
 0.551
EFC89386.1
Malic enzyme, NAD binding domain protein; KEGG: nme:NMB0671 1.4e-221 NAD; malate oxidoreductase K00027.
     
 0.477
EFC89861.1
Phospholipase, patatin family; KEGG: reh:H16_B0344 8.9e-29 phospholipase.
       0.467
EFC89705.1
AMP-binding enzyme; KEGG: nme:NMB1555 8.4e-270 long-chain-fatty-acid--CoA ligase K01897; Psort location: CytoplasmicMembrane, score: 9.82.
      
 0.442
Your Current Organism:
Neisseria mucosa
NCBI taxonomy Id: 546266
Other names: N. mucosa ATCC 25996, Neisseria mucosa ATCC 25996, Neisseria mucosa str. ATCC 25996, Neisseria mucosa strain ATCC 25996
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.